The role of neurosteroids in posttraumatic stress disorder and alcohol use disorder: A review of 10 years of clinical literature and treatment implications

MKR Peltier, TL Verplaetse, M Altemus… - Frontiers in …, 2024 - Elsevier
Rates of alcohol use disorder (AUD) are increasing in men and women and there are high
rates of concurrent posttraumatic stress disorder (PTSD) and AUD. AUD and PTSD …

Changes in the serum concentration levels of serotonin, tryptophan and cortisol among stress-resilient and stress-susceptible individuals after experiencing traumatic …

EA Ogłodek - International Journal of Environmental Research and …, 2022 - mdpi.com
Background: Stress is a common response to many environmental adversities. However,
once dysregulated, this reaction can lead to psychiatric illnesses, such as post-traumatic …

Melatonin alleviates PTSD-like behaviors and restores serum GABA and cortisol levels in mice

Z Xu, W Li, Y Sun, W Jin, L Yu, J Yang, Q Wang - Psychopharmacology, 2023 - Springer
Rationale Melatonin is an endogenous hormone which modulates sleep-wake cycles.
Previous studies have found a close correlation between melatonin and post-traumatic …

Integrated proteomic and metabolomic profiling of lymph after trauma-induced hypercoagulopathy and antithrombotic therapy

Y Zheng, P Wang, L Cong, Q Shi, Y Zhao, YJ Wang - Thrombosis Journal, 2024 - Springer
Background Routine coagulation tests are not widely accepted diagnostic criteria of trauma-
induced hypercoagulopathy (TIH) due to insensitivity. Lymphatic vessels drain …

PTSD biomarkers: Neuroendocrine signaling to epigenetic variants.

A Sbisa, K Graham, E Lawrence-Wood… - Advances in Clinical …, 2024 - europepmc.org
Posttraumatic stress disorder (PTSD) is characterized by exposure to traumatic events and
involves symptom domains such as intrusive thoughts, avoidant behaviors, negative mood …

The Neurosteroid Response to Stress: A Potential Treatment for PTSD and Contributor to Intrusive Memories

K Amir Hamzah - 2024 - eprints.qut.edu.au
This thesis investigates whether the biomarker allopregnanolone plays a role in the
formation of intrusive memories, a core symptom of Post Traumatic Stress Disorder (PTSD) …