Worldwide, familial and epidemiological studies have generated considerable evidence of
an inherited component to prostate cancer. Indeed, rare highly penetrant genetic mutations …

One of the strongest risk factors for prostate cancer is a family history of the disease.
Germline mutations in the breast cancer predisposition gene 2 (BRCA2) are the genetic …

Genome-wide association studies (GWAS) and fine-mapping efforts to date have identified
more than 100 prostate cancer (PrCa)-susceptibility loci. We meta-analyzed genotype data …

Genome-wide association studies (GWAS) have identified 76 variants associated with
prostate cancer risk predominantly in populations of European ancestry. To identify …

Prostate cancer is the most frequently diagnosed cancer in males in developed countries. To
identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a …

Prostate cancer (PrCa) is the most frequently diagnosed male cancer in developed
countries. We conducted a multi-stage genome-wide association study for PrCa and …

Analysis of 4,405 variants in 89,050 European subjects from 41 case-control studies
identified three independent association signals for estrogen-receptor-positive tumors at …

Diffuse large B cell lymphoma (DLBCL) is the most common lymphoma subtype and is
clinically aggressive. To identify genetic susceptibility loci for DLBCL, we conducted a meta …

We report targeted sequencing of 63 known prostate cancer risk regions in a multi-ancestry
study of 9,237 men and use the data to explore the contribution of low-frequency variation to …

Genome-wide association studies (GWAS) have revolutionized the field of cancer genetics,
but the causal links between increased genetic risk and onset/progression of disease …