Microglia activation is observed in various neurodegenerative diseases. Recent advances in
single-cell technologies have revealed that these reactive microglia were with high spatial …

Mesenchymal stromal cells are multipotent cells that are being used to treat a variety of
medical conditions. Over the past decade, there has been considerable excitement about …

Alzheimer's disease is characterized by the histopathological presence of amyloid-β
plaques and tau-containing neurofibrillary tangles. Microglial activation is also a recognized …

Multiple system atrophy (MSA) is an orphan, fatal, adult-onset neurodegenerative disorder of
uncertain etiology that is clinically characterized by various combinations of parkinsonism …

Multiple system atrophy (MSA) is a rare oligodendroglial α-synucleinopathy characterized by
neurodegeneration in striatonigral and olivopontocerebellar regions and autonomic brain …

Microglial cells are the immune cells in the CNS and represent approximately 10% of the
total brain cell population. Their morphologic characterization by Pio del Rio-Hortega was …

Background The role of both microglial activation and alpha-synuclein deposition in
Parkinson's disease remain unclear. We have tested the hypothesis that if microglia play a …

Z. Ahmed, YT Asi, A. Sailer, AJ Lees, H. Houlden, T. Revesz and JL Holton (2012)
Neuropathology and Applied Neurobiology38, 4–24 The neuropathology, pathophysiology …

Abstract α-Synucleinopathies (ASP) comprise adult-onset, progressive neurodegenerative
disorders such as Parkinson's disease (PD), dementia with Lewy bodies (DLB) and multiple …

Microglia are the main immune cells in the brain, playing a role in both physiological and
pathological conditions. Microglial involvement in neurodegenerative diseases is well …