Lipid-based nanovesicular drug delivery systems
In designing a new drug, considering the preferred route of administration, various
requirements must be fulfilled. Active molecules pharmacokinetics should be reliable with a …
requirements must be fulfilled. Active molecules pharmacokinetics should be reliable with a …
[HTML][HTML] Niosome as a promising tool for increasing the effectiveness of anti-inflammatory compounds
Niosomes are drug delivery systems with widespread applications in pharmaceutical
research and the cosmetic industry. Niosomes are vesicles of one or more bilayers made of …
research and the cosmetic industry. Niosomes are vesicles of one or more bilayers made of …
Optimization and characterization of tannic acid loaded niosomes for enhanced antibacterial and anti-biofilm activities
F Heidari, I Akbarzadeh, D Nourouzian… - Advanced Powder …, 2020 - Elsevier
The purpose of this study was to prepare and characterize an optimized system of tannic
acid-loaded niosomes as a potential carrier for antibacterial and anti-biofilm delivery. The …
acid-loaded niosomes as a potential carrier for antibacterial and anti-biofilm delivery. The …
Development of provesicular nanodelivery system of curcumin as a safe and effective antiviral agent: statistical optimization, in vitro characterization, and antiviral …
Curcumin is a natural compound that has many medical applications. However, its low
solubility and poor stability could impede its clinical applications. The present study aimed to …
solubility and poor stability could impede its clinical applications. The present study aimed to …
Construction and characterization of a novel Tenofovir-loaded PEGylated niosome conjugated with TAT peptide for evaluation of its cytotoxicity and anti-HIV effects
In recent years, nanocarriers have become potent drug delivery system candidates,
especially in anti-HIV therapies. Meanwhile, using cell-penetrating peptides such as TAT for …
especially in anti-HIV therapies. Meanwhile, using cell-penetrating peptides such as TAT for …
PEGylated Lipid Polymeric Nanoparticle–Encapsulated Acyclovir for In Vitro Controlled Release and Ex Vivo Gut Sac Permeation
S Mahmood, KC Kiong, CS Tham, TC Chien… - Aaps Pharmscitech, 2020 - Springer
Currently, pharmaceutical research is directed wide range for developing new drugs for oral
administration to target disease. Acyclovir formulation is having common issues of short half …
administration to target disease. Acyclovir formulation is having common issues of short half …
Oral proniosomal amitriptyline and liraglutide for management of diabetic neuropathy: Exceptional control over hyperglycemia and neuropathic pain
Exploitation of nanocarriers provides a compartment for enclosing drugs to protect them from
degradation and potentiate their therapeutic efficiency. In the current study, amitriptyline-and …
degradation and potentiate their therapeutic efficiency. In the current study, amitriptyline-and …
Proniosomal gel for topical delivery of rutin: Preparation, physicochemical characterization and in vitro toxicological profile using 3D reconstructed human epidermis …
I Pinzaru, A Tanase, V Enatescu, D Coricovac… - Antioxidants, 2021 - mdpi.com
Rutin (Rut) is a natural flavonol, well-known for its broad-spectrum of therapeutic effects,
including antioxidant and antitumoral activities; still, it has a reduced clinical outcome due to …
including antioxidant and antitumoral activities; still, it has a reduced clinical outcome due to …
[HTML][HTML] Formulation of Glibenclamide proniosomes for oral administration: Pharmaceutical and pharmacodynamics evaluation
Glibenclamide (GB), oral antidiabetic sulfonylurea, is used in the management of diabetes
mellitus type II. It suffers from low bioavailability due to low water solubility. This work aimed …
mellitus type II. It suffers from low bioavailability due to low water solubility. This work aimed …
Design and development of a proniosomal transdermal drug delivery system of caffeine for management of migraine: In vitro characterization, 131I-radiolabeling and …
MH Aboumanei, AF Mahmoud - Process Biochemistry, 2020 - Elsevier
Caffeine is a naturally occurring alkaloid compound which is widely used alone or in
combination in the treatment of migraine. The short elimination half life of caffeine (3− 5 h) …
combination in the treatment of migraine. The short elimination half life of caffeine (3− 5 h) …