Excessive intake of sugar: An accomplice of inflammation

X Ma, F Nan, H Liang, P Shu, X Fan, X Song… - Frontiers in …, 2022 - frontiersin.org
High sugar intake has long been recognized as a potential environmental risk factor for
increased incidence of many non-communicable diseases, including obesity, cardiovascular …

Molecular aspects of fructose metabolism and metabolic disease

MA Herman, MJ Birnbaum - Cell metabolism, 2021 - cell.com
Excessive sugar consumption is increasingly considered as a contributor to the emerging
epidemics of obesity and the associated cardiometabolic disease. Sugar is added to the diet …

Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate

S Zhao, C Jang, J Liu, K Uehara, M Gilbert, L Izzo… - Nature, 2020 - nature.com
Consumption of fructose has risen markedly in recent decades owing to the use of sucrose
and high-fructose corn syrup in beverages and processed foods, and this has contributed to …

Molecular pathways of nonalcoholic fatty liver disease development and progression

F Bessone, MV Razori, MG Roma - Cellular and Molecular Life Sciences, 2019 - Springer
Nonalcoholic fatty liver disease (NAFLD) is a main hepatic manifestation of metabolic
syndrome. It represents a wide spectrum of histopathological abnormalities ranging from …

The role of the microbiome in NAFLD and NASH

AA Kolodziejczyk, D Zheng, O Shibolet… - EMBO molecular …, 2019 - embopress.org
Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of cardiometabolic
syndrome, which often also includes obesity, diabetes, and dyslipidemia. It is rapidly …

The links between the gut microbiome and non-alcoholic fatty liver disease (NAFLD)

Z Safari, P Gérard - Cellular and Molecular Life Sciences, 2019 - Springer
NAFLD is currently the main cause of chronic liver disease in developed countries, and the
number of NAFLD patients is growing worldwide. NAFLD often has similar symptoms to …

Treatment of NAFLD with diet, physical activity and exercise

M Romero-Gómez, S Zelber-Sagi, M Trenell - Journal of hepatology, 2017 - Elsevier
Lifestyle intervention can be effective when treating non-alcoholic fatty liver diseases
(NAFLD) patients. Weight loss decreases cardiovascular and diabetes risk and can also …

Fructose and sugar: A major mediator of non-alcoholic fatty liver disease

T Jensen, MF Abdelmalek, S Sullivan, KJ Nadeau… - Journal of …, 2018 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic
syndrome; its rising prevalence parallels the rise in obesity and diabetes. Historically …

The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)

E Buzzetti, M Pinzani, EA Tsochatzis - Metabolism, 2016 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent and represents a growing
challenge in terms of prevention and treatment. Despite its high prevalence, only a small …

The role of the gut microbiota in NAFLD

C Leung, L Rivera, JB Furness… - … reviews Gastroenterology & …, 2016 - nature.com
NAFLD is now the most common cause of liver disease in Western countries. This Review
explores the links between NAFLD, the metabolic syndrome, dysbiosis, poor diet and gut …