Role of insulin resistance in endothelial dysfunction

R Muniyappa, JR Sowers - Reviews in Endocrine and Metabolic Disorders, 2013 - Springer
Insulin resistance is frequently associated with endothelial dysfunction and has been
proposed to play a major role in cardiovascular diseases. Insulin exerts pro-and anti …

Endothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications

CE Tabit, WB Chung, NM Hamburg, JA Vita - Reviews in Endocrine and …, 2010 - Springer
Cardiovascular disease is a major complication of diabetes mellitus, and improved
strategies for prevention and treatment are needed. Endothelial dysfunction contributes to …

Cardiovascular actions of insulin

R Muniyappa, M Montagnani, KK Koh… - Endocrine …, 2007 - academic.oup.com
Insulin has important vascular actions to stimulate production of nitric oxide from
endothelium. This leads to capillary recruitment, vasodilation, increased blood flow, and …

Clinical evaluation of blood pressure lowering, endothelial function improving, hypolipidemic and anti‐inflammatory effects of pomegranate juice in hypertensive …

S Asgary, A Sahebkar, MR Afshani… - Phytotherapy …, 2014 - Wiley Online Library
Pomegranate (Punica granatum L.) juice (PJ) contains different types of antioxidants and
bioactive polyphenols and has been reported to promote cardiovascular health through …

Arterial aging: is it an immutable cardiovascular risk factor?

SS Najjar, A Scuteri, EG Lakatta - Hypertension, 2005 - Am Heart Assoc
Age is the dominant risk factor for cardiovascular diseases. However, until recently,
convincing mechanistic or molecular explanations for the increased cardiovascular risks …

Endothelial function and dysfunction. Part II: Association with cardiovascular risk factors and diseases. A statement by the Working Group on Endothelins and …

H Brunner, JR Cockcroft, J Deanfield… - Journal of …, 2005 - journals.lww.com
Dysfunction of the vascular endothelium is a hallmark of most conditions that are associated
with atherosclerosis and is therefore held to be an early feature in atherogenesis. However …

Noninvasive assessment of subclinical atherosclerosis in children and adolescents: recommendations for standard assessment for clinical research: a scientific …

EM Urbina, RV Williams, BS Alpert, RT Collins… - …, 2009 - Am Heart Assoc
Deterioration in endothelial function and arterial stiffness are early events in the
development of cardiovascular diseases. In adults, noninvasive measures of atherosclerosis …

Erectile dysfunction in diabetes mellitus

LS Malavige, JC Levy - The journal of sexual medicine, 2009 - academic.oup.com
Introduction Type 2 diabetes is reaching pandemic levels and young-onset type 2 diabetes
is becoming increasingly common. Erectile dysfunction (ED) is a common and distressing …

Endothelial dysfunction in obesity and insulin resistance: a road to diabetes and heart disease

AE Caballero - Obesity research, 2003 - Wiley Online Library
Obesity, insulin resistance, and endothelial dysfunction closely coexist throughout the
natural history of type 2 diabetes. They all can be identified not only in people with type 2 …

Improvement of early vascular changes and cardiovascular risk factors in obese children after a six-month exercise program

AA Meyer, G Kundt, U Lenschow… - Journal of the American …, 2006 - jacc.org
Objectives: The present study aimed to assess the effect of a 6-month exercise program in
obese children on flow-mediated vasodilation (FMD) carotid intima-media thickness (IMT) …