ABSTRACT Interleukin 10 (IL-10) is a cytokine with potent anti-inflammatory properties that
plays a central role in limiting host immune response to pathogens, thereby preventing …

The IL-10 family of cytokines consists of nine members: IL-10, IL-19, IL-20, IL-22, IL-24, IL-
26, and the more distantly related IL-28A, IL-28B, and IL-29. Evolutionarily, IL-10 family …

The current paradigm of inflammatory bowel diseases (IBD), both Crohn's disease (CD) and
ulcerative colitis (UC), involves the interaction between environmental factors in the …

Mice with targeted deletion of the gene for interleukin-10 (IL-10) spontaneously develop
enterocolitis when maintained in conventional conditions but develop only colitis when kept …

Inflammatory bowel disease: Etiology and pathogenesis - ScienceDirect Skip to main contentSkip
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In recent years the status of the inflammatory bowel diseases (IBDs) as canonical
autoimmune diseases has risen steadily with the recognition that these diseases are, at their …

Commensal microflora (normal microflora, indigenous microbiota) consists of those micro-
organisms, which are present on body surfaces covered by epithelial cells and are exposed …

Inflammatory Bowel Disease (IBD) represents a group of idiopathic disorders characterized
by chronic or recurring inflammation of the gastrointestinal tract. While the exact etiology of …

Cytokines are critical in regulating unresponsiveness versus immunity towards enteric
antigens derived from the intestinal flora and ingested food. There is increasing evidence …

That we live with numerous bacteria in our gut without any adverse effects is a remarkable
feat by the body's immune system, particularly considering the wealth of sensing and effector …