Oxidative damage to macromolecules in human Parkinson disease and the rotenone model
LH Sanders, JT Greenamyre - Free Radical Biology and Medicine, 2013 - Elsevier
Parkinson disease (PD), the most common neurodegenerative movement disorder, is
associated with selective degeneration of nigrostriatal dopamine neurons. Although the …
associated with selective degeneration of nigrostriatal dopamine neurons. Although the …
Resveratrol brain delivery for neurological disorders prevention and treatment
Resveratrol (RES) is a natural polyphenolic non-flavonoid compound present in grapes,
mulberries, peanuts, rhubarb and in several other plants. Numerous health effects have …
mulberries, peanuts, rhubarb and in several other plants. Numerous health effects have …
Protective role of apigenin on rotenone induced rat model of Parkinson's disease: Suppression of neuroinflammation and oxidative stress mediated apoptosis
Protective role of apigenin on rotenone induced rat model of Parkinson's disease: Suppression of
neuroinflammation and oxidative stress mediated apoptosis - ScienceDirect Skip to main …
neuroinflammation and oxidative stress mediated apoptosis - ScienceDirect Skip to main …
Targeting Nrf2 signaling pathway and oxidative stress by resveratrol for Parkinson's disease: an overview and update on new developments
Parkinson's disease (PD) as a prevalent neurodegenerative condition impairs motor function
and is caused by the progressive deterioration of nigrostriatal dopaminergic (DAergic) …
and is caused by the progressive deterioration of nigrostriatal dopaminergic (DAergic) …
High-throughput characterization of chemical-associated embryonic behavioral changes predicts teratogenic outcomes
New strategies are needed to address the data gap between the bioactivity of chemicals in
the environment versus existing hazard information. We address whether a high-throughput …
the environment versus existing hazard information. We address whether a high-throughput …
Mechanism for antiParkinsonian effect of resveratrol: Involvement of transporters, synaptic proteins, dendrite arborization, biochemical alterations, ER stress and …
A Singh, AK Yadawa, S Chaturvedi… - Food and Chemical …, 2021 - Elsevier
The present study was undertaken to evaluate the mechanism for antiParkinsonian effect of
resveratrol employing 6-hydroxydopamine (6-OHDA) induced experimental model of …
resveratrol employing 6-hydroxydopamine (6-OHDA) induced experimental model of …
Improved neuroprotective effect of resveratrol nanoparticles as evinced by abrogation of rotenone-induced behavioral deficits and oxidative and mitochondrial …
S Palle, P Neerati - Naunyn-Schmiedeberg's Archives of Pharmacology, 2018 - Springer
The objective of the present study was to evaluate the protective effect of resveratrol
nanoparticles (NRSV) against rotenone-induced neurodegeneration in rats. NRSV were …
nanoparticles (NRSV) against rotenone-induced neurodegeneration in rats. NRSV were …
Catechin, quercetin and taxifolin improve redox and biochemical imbalances in rotenone-induced hepatocellular dysfunction: Relevance for therapy in pesticide …
AC Akinmoladun, CO Oladejo, SS Josiah… - Pathophysiology, 2018 - Elsevier
Hepatotoxicity occurs as a result of adverse effects of some xenobiotics on the liver, which is
often the target tissue of toxicity for environmental chemicals. Rotenone, used as a natural …
often the target tissue of toxicity for environmental chemicals. Rotenone, used as a natural …
Nutri-epigenetics ameliorates blood–brain barrier damage and neurodegeneration in hyperhomocysteinemia: role of folic acid
A Kalani, PK Kamat, S Givvimani, K Brown… - Journal of Molecular …, 2014 - Springer
Epigenetic mechanisms underlying nutrition (nutrition epigenetics) are important in
understanding human health. Nutritional supplements, for example folic acid, a cofactor in …
understanding human health. Nutritional supplements, for example folic acid, a cofactor in …
High-content high-throughput assays for characterizing the viability and morphology of human iPSC-derived neuronal cultures
O Sirenko, J Hesley, I Rusyn… - Assay and drug …, 2014 - liebertpub.com
Abstract Development of quantitative high-throughput in vitro assays that enable
assessment of viability and morphological changes in neuronal cells is an active area of …
assessment of viability and morphological changes in neuronal cells is an active area of …