Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4‐hydroxy‐2‐nonenal

A Ayala, MF Muñoz, S Argüelles - Oxidative medicine and …, 2014 - Wiley Online Library
Lipid peroxidation can be described generally as a process under which oxidants such as
free radicals attack lipids containing carbon‐carbon double bond (s), especially …

Molecular mechanism of diabetic neuropathy and its pharmacotherapeutic targets

S Dewanjee, S Das, AK Das, N Bhattacharjee… - European journal of …, 2018 - Elsevier
Diabetic neuropathy is regarded as one of the most debilitating outcomes of diabetes
mellitus and may cause pain, decreased motility, and even amputation. Diabetic neuropathy …

Emerging biomarkers, tools, and treatments for diabetic polyneuropathy

GJ Bönhof, C Herder, A Strom, N Papanas… - Endocrine …, 2019 - academic.oup.com
Diabetic neuropathy, with its major clinical sequels, notably neuropathic pain, foot ulcers,
and autonomic dysfunction, is associated with substantial morbidity, increased risk of …

[HTML][HTML] Oxidative stress and nerve damage: role in chemotherapy induced peripheral neuropathy

A Areti, VG Yerra, VGM Naidu, A Kumar - Redox biology, 2014 - Elsevier
Peripheral neuropathy is a severe dose limiting toxicity associated with cancer
chemotherapy. Ever since it was identified, the clear pathological mechanisms underlying …

[HTML][HTML] Diabetic neuropathy

EL Feldman, BC Callaghan, R Pop-Busui… - Nature reviews Disease …, 2019 - nature.com
The global epidemic of prediabetes and diabetes has led to a corresponding epidemic of
complications of these disorders. The most prevalent complication is neuropathy, of which …

Diabetic neuropathy: cellular mechanisms as therapeutic targets

AM Vincent, BC Callaghan, AL Smith… - Nature Reviews …, 2011 - nature.com
In patients with diabetes, nerve injury is a common complication that leads to chronic pain,
numbness and substantial loss of quality of life. Good glycemic control can decrease the …

Diabetic neuropathy and neuropathic pain: a (con) fusion of pathogenic mechanisms?

NA Calcutt - Pain, 2020 - journals.lww.com
Neuropathy will afflict over half of the estimated 460 million people worldwide who have
diabetes, 303 of whom approximately onethird will also develop neuropathic pain. 2 The …

Mechanisms of diabetic foot ulceration: A review

H Deng, B Li, Q Shen, C Zhang, L Kuang… - Journal of …, 2023 - Wiley Online Library
Diabetic foot ulcers (DFUs) are associated with complex pathogenic factors and are
considered a serious complication of diabetes. The potential mechanisms underlying DFUs …

Pathogenesis of diabetic neuropathy: focus on neurovascular mechanisms

PS Van Dam, MA Cotter, B Bravenboer… - European journal of …, 2013 - Elsevier
Neuropathies of the peripheral and autonomic nervous systems affect up to half of all people
with diabetes, and are major risk factors for foot ulceration and amputation. The aetiology is …

Metabolic memory phenomenon in diabetes mellitus: achieving and perspectives

A Berezin - Diabetes & Metabolic Syndrome: Clinical Research & …, 2016 - Elsevier
Diabetes mellitus (DM) exhibits raised prevalence worldwide. There is a large body of
evidence regarding the incidence of DM closely associates with cardiovascular (CV) …