Toxin-linked mobile genetic elements in major enteric bacterial pathogens

S Panwar, S Kumari, J Verma, S Bakshi… - Gut …, 2023 - cambridge.org
One of the fascinating outcomes of human microbiome studies adopting multi-omics
technology is its ability to decipher millions of microbial encoded functions in the most …

The cell wall lipoprotein CD1687 acts as a DNA binding protein during deoxycholate-induced biofilm formation in Clostridioides difficile

E Auria, L Hunault, P England, M Monot… - npj Biofilms and …, 2023 - nature.com
The ability of bacterial pathogens to establish recurrent and persistent infections is
frequently associated with their ability to form biofilms. Clostridioides difficile infections have …

Predictive regulatory and metabolic network models for systems analysis of Clostridioides difficile

ML Arrieta-Ortiz, SRC Immanuel, S Turkarslan, WJ Wu… - Cell host & …, 2021 - cell.com
We present predictive models for comprehensive systems analysis of Clostridioides difficile,
the etiology of pseudomembranous colitis. By leveraging 151 published transcriptomes, we …

[HTML][HTML] Extracellular succinate induces spatially organized biofilm formation in Clostridioides difficile

E Auria, J Deschamps, R Briandet, B Dupuy - Biofilm, 2023 - Elsevier
Clostridioides difficile infection associated to gut microbiome dysbiosis is the leading cause
for nosocomial diarrhea. The ability of C. difficile to form biofilms has been progressively …

A synthetic biology approach to assemble and reboot clinically relevant Pseudomonas aeruginosa tailed phages

T Ipoutcha, R Racharaks, S Huttelmaier… - Microbiology …, 2024 - Am Soc Microbiol
The rise in the frequency of antibiotic resistance has made bacterial infections, specifically
Pseudomonas aeruginosa, a cause for greater concern. Phage therapy is a promising …

Deletion of prophages in Clostridioides difficile

R Kalarus - 2022 - uhra.herts.ac.uk
Clostridioides difficile (C. difficile) formally known as Clostridium difficile, is a Gram-positive
spore forming anaerobe responsible for almost all cases of pseudomembranous colitis and …