Renal transplantation is currently the most effective treatment for end-stage renal disease.
However, chronic antibody-mediated rejection (cABMR) remains a serious obstacle for the …

The immune system response of transplant recipients is the main cause of allograft rejection;
therefore, its suppression seems crucial. Nevertheless, immunosuppressive agents are …

Background We recently demonstrated that donor-derived modified immune cells (MICs)—
PBMCs that acquire immunosuppressive properties after a brief treatment—induced specific …

Introduction The human immune system contains cells with either effector/memory or
regulatory functions. Besides the well-established CD4+ CD25hiCD127lo regulatory T cells …

Background Antibody-mediated rejection (AMR) occupies a major position for chronic
rejection after kidney transplantation. Regulatory B cell (Breg) has been reported to have an …

Abstract Problem Interleukin 35 (IL‐35) is involved in the pathogenesis of endometriosis by
suppressing immunoreaction and promoting endometrial cell proliferation. It may also be an …

Background. Kidney transplantation is the best treatment option for end stage renal disease
(ESRD), but graft rejection is still a big obstacle that occurs in spite of immunosuppressive …

Objective: Chronic rejection remains the main factor that influence long-term survival of
patients after heart transplantation. Interleukin-10 (IL-10) play critical role in macrophages …

Background. Regulatory T cells (Tregs) and recent thymic emigrants (RTEs) have an
essential role in the regulation of allogeneic immune responses. However, their …

Background: The role of the cellular level in kidney transplant rejection is unclear, and single-
cell RNA sequencing (scRNA-seq) can reveal the single-cell landscape behind rejection of …