Microbial infections are controlled by host inflammatory responses that are initiated by
innate immune receptors after recognition of conserved microbial products. As inflammation …

Aging-related neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's
disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS), are …

Salmonella injects over 40 virulence factors, termed effectors, into host cells to subvert
diverse host cellular processes. Of these 40 Salmonella effectors, at least 25 have been …

The food-borne bacterial pathogen Salmonella Typhimurium uses a type III protein secretion
system to deliver multiple proteins into host cells. These secreted effectors modulate the …

The major function of the mammalian immune system is to prevent and control infections
caused by enteropathogens that collectively have altered human destiny. In fact, as the …

Primary cilia are nearly ubiquitous organelles that transduce molecular and mechanical
signals. Although the basic structure of the cilium and the cadre of genes that contribute to …

Ras-related protein in brain (Rab) proteins are dysregulated in cancer cells and affect the
proliferation and metastasis of cancer cells, thereby reducing the survival rate of cancer …

Salmonella is a major foodborne pathogen of both animals and humans. This bacterium is
responsible for considerable morbidity and mortality world-wide. Different serovars of this …

Cervical cancer (CC) is a gynecological cancer, which has become the second malignant
tumor with mortality in developing countries. The purpose of current study was to explore the …

Energy status is linked to the production of reactive oxygen species (ROS) in macrophages,
which is elevated in obesity. However, it is unclear how ROS production is upregulated in …