Salmonella Typhimurium and inflammation: a pathogen-centric affair
JE Galán - Nature Reviews Microbiology, 2021 - nature.com
Microbial infections are controlled by host inflammatory responses that are initiated by
innate immune receptors after recognition of conserved microbial products. As inflammation …
innate immune receptors after recognition of conserved microbial products. As inflammation …
Roles of long non-coding RNAs in the development of aging-related neurodegenerative diseases
YQ Ni, H Xu, YS Liu - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Aging-related neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's
disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS), are …
disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS), are …
Speaking the host language: how Salmonella effector proteins manipulate the host
TD Pillay, SU Hettiarachchi, J Gan… - …, 2023 - microbiologyresearch.org
Salmonella injects over 40 virulence factors, termed effectors, into host cells to subvert
diverse host cellular processes. Of these 40 Salmonella effectors, at least 25 have been …
diverse host cellular processes. Of these 40 Salmonella effectors, at least 25 have been …
The Salmonella effector protein SopD targets Rab8 to positively and negatively modulate the inflammatory response
H Lian, K Jiang, M Tong, Z Chen, X Liu, JE Galán… - Nature …, 2021 - nature.com
The food-borne bacterial pathogen Salmonella Typhimurium uses a type III protein secretion
system to deliver multiple proteins into host cells. These secreted effectors modulate the …
system to deliver multiple proteins into host cells. These secreted effectors modulate the …
Immune evasion and persistence in enteric bacterial pathogens
M J. Worley - Gut Microbes, 2023 - Taylor & Francis
The major function of the mammalian immune system is to prevent and control infections
caused by enteropathogens that collectively have altered human destiny. In fact, as the …
caused by enteropathogens that collectively have altered human destiny. In fact, as the …
Identification of a heterogeneous and dynamic ciliome during embryonic development and cell differentiation
KH Elliott, SK Balchand, CL Bonatto Paese… - …, 2023 - journals.biologists.com
Primary cilia are nearly ubiquitous organelles that transduce molecular and mechanical
signals. Although the basic structure of the cilium and the cadre of genes that contribute to …
signals. Although the basic structure of the cilium and the cadre of genes that contribute to …
Rab8A promotes breast cancer progression by increasing surface expression of Tropomyosin-related kinase B
Y Liu, Z Zhang, X Gao, Q Ma, Z Yu, S Huang - Cancer Letters, 2022 - Elsevier
Ras-related protein in brain (Rab) proteins are dysregulated in cancer cells and affect the
proliferation and metastasis of cancer cells, thereby reducing the survival rate of cancer …
proliferation and metastasis of cancer cells, thereby reducing the survival rate of cancer …
Salmonella Bloodstream Infections
MJ Worley - Tropical Medicine and Infectious Disease, 2023 - mdpi.com
Salmonella is a major foodborne pathogen of both animals and humans. This bacterium is
responsible for considerable morbidity and mortality world-wide. Different serovars of this …
responsible for considerable morbidity and mortality world-wide. Different serovars of this …
Circular RNA 0001823 aggravates the growth and metastasis of the cervical cancer cells through modulating the microRNA-613/RAB8A axis
H Ji, N Hu - Bioengineered, 2022 - Taylor & Francis
Cervical cancer (CC) is a gynecological cancer, which has become the second malignant
tumor with mortality in developing countries. The purpose of current study was to explore the …
tumor with mortality in developing countries. The purpose of current study was to explore the …
TBC1D1 is an energy-responsive polarization regulator of macrophages via governing ROS production in obesity
Q Wang, P Rong, W Zhang, X Yang, L Chen… - Science China Life …, 2024 - Springer
Energy status is linked to the production of reactive oxygen species (ROS) in macrophages,
which is elevated in obesity. However, it is unclear how ROS production is upregulated in …
which is elevated in obesity. However, it is unclear how ROS production is upregulated in …