Self-assembling nucleic acid nanostructures functionalized with aptamers

A Krissanaprasit, CM Key, S Pontula… - Chemical …, 2021 - ACS Publications
Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …

Electrochemical DNA sensors based on the use of gold nanoparticles: a review on recent developments

PA Rasheed, N Sandhyarani - Microchimica Acta, 2017 - Springer
Electrochemical DNA sensors represent a simple, accurate and economical platform for
DNA detection. Gold nanoparticles are known to be efficient labels in electrochemical …

Nucleic acids modulate liquidity and dynamics of artificial membraneless organelles

J Liu, F Zhorabek, Y Chau - ACS Macro Letters, 2022 - ACS Publications
Liquid–liquid phase separation (LLPS) emerges as a fundamental underlying mechanism
for the biological organization, especially the formation of membraneless organelles (MLOs) …

A novel label-free electrochemical miRNA biosensor using methylene blue as redox indicator: application to breast cancer biomarker miRNA-21

HA Rafiee-Pour, M Behpour, M Keshavarz - Biosensors and bioelectronics, 2016 - Elsevier
Small noncoding microRNAs (miRNAs) have emerged as ideal noninvasive biomarkers for
early-phase cancer detection. In this report, a label-free and simple electrochemical miRNA …

Ratiometric electrochemical aptasensor for ultrasensitive detection of Ochratoxin A based on a dual signal amplification strategy: Engineering the binding of …

C Zhu, D Liu, Y Li, X Shen, S Ma, Y Liu, T You - Biosensors and …, 2020 - Elsevier
A novel ratiometric electrochemical aptasensor was developed for Ochratoxin A (OTA)
detection based on the binding of methylene blue (MB) to DNA with a dual signal …

Molecular flexibility in ab initio drug docking to DNA: binding-site and binding-mode transitions in all-atom Monte Carlo simulations

R Rohs, I Bloch, H Sklenar, Z Shakked - Nucleic acids research, 2005 - academic.oup.com
The dynamics of biological processes depend on the structure and flexibility of the
interacting molecules. In particular, the conformational diversity of DNA allows for large …

Intercalation of organic dye molecules into double-stranded DNA--general principles and recent developments

H Ihmels, D Otto - Supermolecular dye chemistry, 2005 - Springer
Several aspects of the intercalation of organic dyes into DNA are presented. After a
description of general features of intercalation and the analytical evaluation of this binding …

A novel electrochemical detection method for aptamer biosensors

GS Bang, S Cho, BG Kim - Biosensors and bioelectronics, 2005 - Elsevier
A beacon aptamer-based biosensor for the detection of thrombin was developed using
electrochemical transduction method. Gold surface was modified with a beacon aptamer …

Voltammetric determination of DNA hybridization using methylene blue and self-assembled alkanethiol monolayer on gold electrodes

K Kerman, D Ozkan, P Kara, B Meric, JJ Gooding… - Analytica Chimica …, 2002 - Elsevier
An electrochemical DNA biosensor based on the recognition of single stranded DNA
(ssDNA) by hybridization detection with immobilized complementary DNA oligonucleotides …

Ratiometric immunosensor for GP73 detection based on the ratios of electrochemiluminescence and electrochemical signal using DNA tetrahedral nanostructure as …

Y Lin, J Jia, R Yang, D Chen, J Wang, F Luo… - Analytical …, 2019 - ACS Publications
DNA tetrahedron nanostructure (DTNs) has the merits of simple synthesis, high yield,
structural stability, and mechanical rigidity, and its three-dimensional structure provides a …