Microglia-mediated neuroinflammation is a common feature of neurodegenerative diseases
such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis …

Multiple lines of evidence indicate that immune system dysfunction has a role in Parkinson
disease (PD); this evidence includes clinical and genetic associations between autoimmune …

Microglia are resident macrophage-like immune cells in the central nervous system (CNS)
and play a vital role in both physiological and pathological conditions, including restoring …

Sepsis-associated encephalopathy (SAE) is a cognitive impairment associated with sepsis
that occurs in the absence of direct infection in the central nervous system or structural brain …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by protein
aggregation in the brain. Recent studies have revealed the critical role of microglia in AD …

Neuroinflammatory changes play a pivotal role in the progression of Parkinson's disease
(PD) pathogenesis. Recent findings have suggested that activated microglia may polarize …

Many agents developed for neuroprotective treatment of Parkinson disease (PD) have
shown great promise in the laboratory, but none have translated to positive results in …

Parkinson disease is an inexorably progressive neurodegenerative disorder. Multiple
attempts have been made to establish therapies for Parkinson disease which provide …

Traumatic brain injury (TBI) is a serious disease that threatens life and health of people. It
poses a great economic burden on the healthcare system. Thus, seeking effective therapy to …

Background Discoveries that microglia-mediated neuroinflammation is involved in the
pathological process of depression provided a new strategy for novel antidepressant …