Akt-GSK3β-mPTP pathway regulates the mitochondrial dysfunction contributing to odontoblasts apoptosis induced by glucose oxidative stress
D Wu, L Yan, C Zheng, X Ren, Y Pan, S Huang… - Cell Death …, 2022 - nature.com
Diabetes Mellitus can cause dental pulp cells apoptosis by oxidative stress, and affect the
integrity and function of dental pulp tissue. Mitochondria are the main attack targets of …
integrity and function of dental pulp tissue. Mitochondria are the main attack targets of …
Protective effect of quercetin on alteration of antioxidant genes expression and histological changes in the dental pulp of the streptozotocin-diabetic rats
A Bagheri, S Ebrahimpour, N Nourbakhsh… - Archives of Oral …, 2021 - Elsevier
Objective We aimed to assess the effect of quercetin as one of the most common
polyphenols with anti-inflammatory and antioxidant properties on expression levels of …
polyphenols with anti-inflammatory and antioxidant properties on expression levels of …
Effects of diabetes mellitus on dental pulp: A systematic review of in vivo and in vitro studies
RMN Pimenta, AH dos Reis‐Prado… - Oral …, 2024 - Wiley Online Library
Objectives This systematic review (PROSPERO CRD42021227711) evaluated the influence
of diabetes mellitus (DM) on the response of the pulp tissue and in the pulp cells behaviour …
of diabetes mellitus (DM) on the response of the pulp tissue and in the pulp cells behaviour …
Effects of glycation end‐products on the dental pulp in patients with type 2 diabetes
S Alsamahi, TJ Milne… - International …, 2023 - Wiley Online Library
Aim This ex vivo study aimed to compare protein expression of advanced glycation end‐
products (AGE) and receptor (RAGE), and the levels of selected genes associated with …
products (AGE) and receptor (RAGE), and the levels of selected genes associated with …
Histological Aspects Regarding Dental Pulp of Diabetic Patients
CG Puşcaşu, CL Ștefănescu, RM Murineanu… - Applied Sciences, 2021 - mdpi.com
Background: The possible histological changes in dental pulp in teeth of diabetic patients
are important to be understood, as the clinician will consider the best treatment choice for …
are important to be understood, as the clinician will consider the best treatment choice for …
Type 2 diabetes aggravates periodontitis‐induced pathological changes in the dental pulp
T Yang, B Zhou, Z Shan, L Hu - Oral Diseases, 2023 - Wiley Online Library
Objectives The inner mechanism of how diabetes affects dental pulp of patients with
periodontitis has seldom been reported. We collected clinical samples and explored the …
periodontitis has seldom been reported. We collected clinical samples and explored the …
[HTML][HTML] Impaired pulp healing associated with underlying disorders in the dental pulp of rats with type 2 diabetes
S Tao, T Yang, JN Zhou, Q Zhang - Journal of Dental Sciences, 2024 - Elsevier
Background/purpose Type 2 diabetes mellitus (T2DM), characterized by hyperglycemia, is a
systematic disease affecting structure and healing ability in various tissues. This study aimed …
systematic disease affecting structure and healing ability in various tissues. This study aimed …
[HTML][HTML] Mitochondrial reactive oxygen species promote mitochondrial damage in high glucose-induced dysfunction and apoptosis of human dental pulp cells
S Tao, T Yang, Y Yin, Q Zhang - Journal of Dental Sciences, 2024 - Elsevier
Background/purpose High glucose (HG)-induced aberrant proliferation, apoptosis and
odontoblastic differentiation of dental pulp cells (DPCs) have been implicated in the …
odontoblastic differentiation of dental pulp cells (DPCs) have been implicated in the …
[HTML][HTML] Hyporesponsiveness of nerves of the dental pulp in type 2 diabetes–An enigmatic oral sign
SM Fenn, M Jacob, RP Thangavelu… - Journal of Indian …, 2023 - journals.lww.com
Background: Type 2 diabetes, the most predominant type of diabetes, can lead to
complications in the oral cavity and body due to its impact on physiological functioning …
complications in the oral cavity and body due to its impact on physiological functioning …
Pulpal outcomes in orthodontic tooth movement in diabetes mellitus
M Santamaria-Jr, ERA do Nascimento, L Bagne… - Odontology, 2021 - Springer
Diabetes mellitus impairs angiogenesis and tissue reorganization during orthodontic tooth
movement (OTM). Thus, this study evaluated pulpal outcomes in orthodontic tooth …
movement (OTM). Thus, this study evaluated pulpal outcomes in orthodontic tooth …