Large bone defects due to trauma, infections, and tumors are difficult to heal spontaneously
by the body's repair mechanisms and have become a major hindrance to people's daily lives …

Tailing off release in the sustained release of water-insoluble curcumin (Cur) is a significant
challenge in the drug delivery system. As a novel solution, core–shell nanodrug containers …

Poloxamer is a triblock copolymer with amphiphilicity and reversible thermal responsiveness
and has wide application prospects in biomedical applications owing to its multifunctional …

Complicated fractures have always been challenging in orthopaedics. Designing a
multifunctional biomaterial that can contribute to the treatment of fractures using a simple …

Osteoporosis is an age-related metabolic disease that results in limited bone regeneration
capacity and excessive osteoclast activity. After arthroplasty in patients with osteoporosis …

Hydrogel is composed of a three-dimensional network of hydrophilic polymers and can swell
when placed in an aqueous media. Polyvinyl alcohol (PVA) is a common polymer used to …

Cannabidiol (CBD) shows great anti-inflammatory potential; however, the hydrophobicity
and strong first-pass effect of CBD leads to its extremely low oral bioavailability. Poloxamer …

Osteomyelitis is an inflammation of bone tissue usually caused by pyogenic bacteria. The
most recurrent clinical approach consists of bone debridement followed by parenteral …

Mesoporous bioactive glasses (MBGs) are deemed as bone implants for inducing osteoblast
differentiation and preventing bone resorption, however, the damage of peri-implantitis on …

The effect of some modifier oxides (MO) which are Li 2 O, MgO, ZnO and CaO on the
radiation shielding features of B 2 O 3–SiO 2–Na 2 O–ZrO 2-MO (BSNZ-MO) glasses were …