A large body of research supports the notion that regions of the rodent frontal cortex regulate
reinstatement of cocaine seeking after cessation of intravenous cocaine self-administration …

Adolescents are at increased risk to develop substance use disorders and suffer from
relapse throughout life. Targeted weakening of drug-associated memories has been shown …

Rationale Drug use during adolescence results in a life-long risk to develop substance-use
disorders. Adolescent rats are sensitive to different drug-associated cues, compared to …

Alcohol has complex effects on cerebrovascular health. Monitoring the pathology of alcohol
induced cerebrovascular changes in vivo is essential for understanding the mechanism and …

Rationale Drug use during adolescence results in a lifelong risk to develop substance-use
disorders. Adolescent rats are less reactive to cocaine-associated cues compared with …

Exposure to stressors can cause functional disorders and structural damage to the stomach.
Sertraline (SER) is an antidepressant and curcumin (CUR) is a natural compound with many …

Unnecessary risk-taking is a core characteristic of maladaptive behaviors such as addiction
and gambling. Risk is defined as possible exposure to an unfavorable outcome which may …

Manual quantification of activated cells can provide valuable information about stimuli-
induced changes within brain regions; however, this analysis remains time intensive …

Our daily life activities are highly dependent on rewards and their ability to drive our
motivational and goal-directed behaviours. Rewards are essential for all individuals as they …