Mitochondria at the neuronal presynapse in health and disease
MJ Devine, JT Kittler - Nature Reviews Neuroscience, 2018 - nature.com
Synapses enable neurons to communicate with each other and are therefore a prerequisite
for normal brain function. Presynaptically, this communication requires energy and …
for normal brain function. Presynaptically, this communication requires energy and …
Mitochondrial dynamics and their potential as a therapeutic target
BN Whitley, EA Engelhart, S Hoppins - Mitochondrion, 2019 - Elsevier
Mitochondrial dynamics shape the mitochondrial network and contribute to mitochondrial
function and quality control. Mitochondrial fusion and division are integrated into diverse …
function and quality control. Mitochondrial fusion and division are integrated into diverse …
Miro proteins coordinate microtubule‐and actin‐dependent mitochondrial transport and distribution
G López‐Doménech, C Covill‐Cooke… - The EMBO …, 2018 - embopress.org
In the current model of mitochondrial trafficking, Miro1 and Miro2 Rho‐GTP ases regulate
mitochondrial transport along microtubules by linking mitochondria to kinesin and dynein …
mitochondrial transport along microtubules by linking mitochondria to kinesin and dynein …
Mitochondrial morphofunction in mammalian cells
EP Bulthuis, MJW Adjobo-Hermans… - Antioxidants & redox …, 2019 - liebertpub.com
Significance: In addition to their classical role in cellular ATP production, mitochondria are of
key relevance in various (patho) physiological mechanisms including second messenger …
key relevance in various (patho) physiological mechanisms including second messenger …
Therapeutic evaluation of solid lipid nanoparticle of quercetin in pentylenetetrazole induced cognitive impairment of zebrafish
N Rishitha, A Muthuraman - Life sciences, 2018 - Elsevier
Background Quercetin is a major flavonoid in various plants. It possesses the multiple
pharmacological actions like vascular integrity and regulatory action of the blood-brain …
pharmacological actions like vascular integrity and regulatory action of the blood-brain …
Multi-target effects of ß-caryophyllene and carnosic acid at the crossroads of mitochondrial dysfunction and neurodegeneration: from oxidative stress to microglia …
R Iorio, G Celenza, S Petricca - Antioxidants, 2022 - mdpi.com
Inflammation and oxidative stress are interlinked and interdependent processes involved in
many chronic diseases, including neurodegeneration, diabetes, cardiovascular diseases …
many chronic diseases, including neurodegeneration, diabetes, cardiovascular diseases …
Parkin is a disease modifier in the mutant SOD 1 mouse model of ALS
GM Palomo, V Granatiero, H Kawamata… - EMBO molecular …, 2018 - embopress.org
Abstract Mutant Cu/Zn superoxide dismutase (SOD 1) causes mitochondrial alterations that
contribute to motor neuron demise in amyotrophic lateral sclerosis (ALS). When …
contribute to motor neuron demise in amyotrophic lateral sclerosis (ALS). When …
Dynamin‐related protein 1: a critical protein in the pathogenesis of neural system dysfunctions and neurodegenerative diseases
Z Qi, Z Huang, F Xie, L Chen - Journal of cellular physiology, 2019 - Wiley Online Library
Mitochondria play a key role in the maintenance of neuronal function by continuously
providing energy. Here, we will give a detailed review about the recent developments in …
providing energy. Here, we will give a detailed review about the recent developments in …
Peroxisomal fission is modulated by the mitochondrial Rho‐GTPases, Miro1 and Miro2
Peroxisomes are essential for a number of cellular functions, including reactive oxygen
species metabolism, fatty acid β‐oxidation and lipid synthesis. To ensure optimal …
species metabolism, fatty acid β‐oxidation and lipid synthesis. To ensure optimal …
Expression of mitochondrial dysfunction-related genes and pathways in paclitaxel-induced peripheral neuropathy in breast cancer survivors
KM Kober, A Olshen, YP Conley… - Molecular …, 2018 - journals.sagepub.com
Background Paclitaxel is one of the most commonly used drugs to treat breast cancer. Its
major dose-limiting toxicity is paclitaxel-induced peripheral neuropathy (PIPN). PIPN …
major dose-limiting toxicity is paclitaxel-induced peripheral neuropathy (PIPN). PIPN …