Elastin structure, synthesis, regulatory mechanism and relationship with cardiovascular diseases
K Wang, X Meng, Z Guo - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
As the primary component of elastic fibers, elastin plays an important role in maintaining the
elasticity and tensile ability of cardiovascular, pulmonary and many other tissues and …
elasticity and tensile ability of cardiovascular, pulmonary and many other tissues and …
Peripheral blood mononuclear cell secretome for tissue repair
For almost two decades, cell-based therapies have been tested in modern regenerative
medicine to either replace or regenerate human cells, tissues, or organs and restore normal …
medicine to either replace or regenerate human cells, tissues, or organs and restore normal …
[HTML][HTML] Engineered neutrophil apoptotic bodies ameliorate myocardial infarction by promoting macrophage efferocytosis and inflammation resolution
L Bao, G Dou, R Tian, Y Lv, F Ding, S Liu, R Zhao… - Bioactive materials, 2022 - Elsevier
Inflammatory response plays a critical role in myocardial infarction (MI) repair. The
neutrophil apoptosis and subsequent macrophage ingestion can result in inflammation …
neutrophil apoptosis and subsequent macrophage ingestion can result in inflammation …
Mesenchymal stromal cells mediate a switch to alternatively activated monocytes/macrophages after acute myocardial infarction
V Dayan, G Yannarelli, F Billia, P Filomeno… - Basic research in …, 2011 - Springer
Given the established anti-inflammatory properties of mesenchymal stromal cells (MSCs),
we investigated their effect on inflammatory cell infiltration of ischemic cardiac tissue and …
we investigated their effect on inflammatory cell infiltration of ischemic cardiac tissue and …
Analysis of the secretome of apoptotic peripheral blood mononuclear cells: impact of released proteins and exosomes for tissue regeneration
L Beer, M Zimmermann, A Mitterbauer, A Ellinger… - Scientific reports, 2015 - nature.com
We previously showed that, when peripheral blood mononuclear cells (PBMCs) were
stressed with ionizing radiation, they released paracrine factors that showed regenerative …
stressed with ionizing radiation, they released paracrine factors that showed regenerative …
[HTML][HTML] Cell secretome based drug substances in regenerative medicine: when regulatory affairs meet basic science
“Regenerative medicine” or “tissue regeneration” had become to an inspired term recently
since it has been realized in the last decade that many organs such as the skin display …
since it has been realized in the last decade that many organs such as the skin display …
Apoptotic neutrophil-mediated inflammatory microenvironment regulation for the treatment of ARDS
X Liu, Q Qiao, X Li, X Ou, K Cui, B Niu, C Yang, L Kong… - Nano Today, 2023 - Elsevier
Acute respiratory distress syndrome (ARDS) is a critical respiratory disease characterized by
uncontrolled acute lung inflammation with high mortality. At present, effective therapeutic …
uncontrolled acute lung inflammation with high mortality. At present, effective therapeutic …
Regenerative cardiovascular therapies: stem cells and beyond
B Wernly, M Mirna, R Rezar, C Prodinger… - International journal of …, 2019 - mdpi.com
Although reperfusion therapy has improved outcomes, acute myocardial infarction (AMI) is
still associated with both significant mortality and morbidity. Once irreversible myocardial cell …
still associated with both significant mortality and morbidity. Once irreversible myocardial cell …
Cell therapy for human ischemic heart diseases: critical review and summary of the clinical experiences
N Pavo, S Charwat, N Nyolczas, A Jakab… - Journal of molecular and …, 2014 - Elsevier
A decade ago, stem or progenitor cells held the promise of tissue regeneration in human
myocardium, with the expectation that these therapies could rescue ischemic myocyte …
myocardium, with the expectation that these therapies could rescue ischemic myocyte …
Stem cells and regenerative medicine—future perspectives
Stem cell research has expanded at an exponential rate, but its therapeutic applications
have progressed much more slowly. Currently, the research focuses on understanding …
have progressed much more slowly. Currently, the research focuses on understanding …