[HTML][HTML] Computational Workflow to Design Novel Vaccine Candidates and Small-Molecule Therapeutics for Schistosomiasis

EO Balogun, GI Joseph, SC Olabode, NA Dayaso… - Pathogens, 2024 - mdpi.com
Human schistosomiasis, caused by the Schistosoma trematode, is a neglected parasitic
disease affecting over 250 million people worldwide. There is no vaccine, and the single …

Identification of selective plant-derived natural carotenoid and flavonoids as the potential inhibitors of DHHC-mediated protein S-palmitoylation: an in silico study

S Chaturvedi, N Pandya, S Sadhukhan… - Journal of …, 2024 - Taylor & Francis
Protein S-palmitoylation mediated by DHHCs is recognized as a distinct and reversible form
of lipid modification connected with several health perturbations, including …

An immunoinformatics analysis: design of a multi-epitope vaccine against Cryptosporidium hominis by employing heat shock protein triggers the innate and adaptive …

N Pandya, A Kumar - Journal of Biomolecular Structure and …, 2023 - Taylor & Francis
Cryptosporidium hominis, an anthropologically transferred species in the Cryptosporidium
genus, represents many clinical studies in several countries. Its growth in the recent decade …

An immunoinformatic approach for developing a multi-epitope subunit vaccine against Monkeypox virus

AK Nayak, A Chakraborty, S Shukla, N Kumar… - In Silico …, 2024 - Springer
An in-silico approach was implemented to develop a multi-epitope subunit vaccine construct
against the recent outbreak of the Monkeypox virus. The contribution of 10 different antigenic …

De novo design of cathepsin b1 inhibitors as potential anti-schistosomal agents using computational studies

AA Alzain, FA Elbadwi - Advances and Applications in …, 2022 - Taylor & Francis
Background Schistosomiasis is the world's second most devastating disease after malaria
and the leading cause of disease and mortality for more than 200 million people in …

A multi-epitope vaccine candidate developed from unique immunogenic epitopes against Cryptosporidium hominis by utilizing an immunoinformatics-driven …

N Pandya, A Kumar - Journal of Biomolecular Structure and …, 2023 - Taylor & Francis
An immunoinformatics-based strategy is being investigated to identify prospective multi-
subunit vaccine candidates against Cryptosporidium hominis (C. hominis). We used a …

[PDF][PDF] Omics: Applications related to diagnosis, treatment, prevention and control of parasitic diseases. Part II. Helminths

R Diab, S Younis - Parasitologists United Journal, 2022 - journals.ekb.eg
Landscape genomic studies can help define the role of geography and ecology in the
clinical presentation ofparasitic diseases, and consequently provide the choice for accurate …