Resistance to therapy is a frequently observed phenomenon in the treatment of cancer, and
as with other cancer therapeutics, therapies based on oncolytic viruses also face the …

Introduction: Measuring the immediate changes in cells that arise from changing
environmental conditions is crucial to understanding the underlying mechanisms involved …

The most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal
dementia (FTD) is a hexanucleotide repeat expansion in C9orf72 (C9-HRE). While RNA and …

Omics technologies focus on uncovering the complex nature of molecular mechanisms in
cells and organisms, including biomarkers and drug targets discovery. Aiming at these tasks …

Simple Summary This study aims to uncover the contribution of interferon-dependent
antiviral mechanisms preserved in tumor cells to the resistance of glioblastoma multiforme …

Peptide mass shifts were profiled using ultra-tolerant database search strategy for shotgun
proteomics data sets of human glioblastoma cell lines demonstrating strong response to the …

Objective: The main reasons for the poor prognoses of pancreatic adenocarcinoma (PA)
patients are rapid early-stage progression, advanced stage metastasis, and chemotherapy …

A collection of intracranial astrocytomas of different malignancy grades was analyzed for
copy number aberrations (CNA) in order to identify regions that are driving cancer …

Cancer cell lines responded differentially to type I interferon treatment in models of oncolytic
therapy using vesicular stomatitis virus (VSV). Two opposite cases were considered in this …

One of the main goals of quantitative proteomics is molecular profiling of cellular response to
stress at the protein level. To perform this profiling, statistical analysis of experimental data …