Peptide-based subunit vaccines utilise minimal immunogenic components (ie peptides) to
generate highly specific immune responses, without triggering adverse reactions. However …

Toll-like receptors (TLRs) are vital elements of the mammalian immune system that function
by recognizing pathogen-associated molecular patterns (PAMPs), bridging innate and …

Peptide-based vaccines have the potential to overcome the limitations of classical vaccines;
however, their use is hampered by a lack of carriers and adjuvants suitable for human use …

Group A Streptococcus (GAS) infection can cause a variety of diseases in humans, ranging
from common sore throats and skin infections, to more invasive diseases and life …

Background Group A streptococcus (GAS) is a serious human pathogen that affects people
of different ages and socio-economic levels. Although vaccination is potentially one of the …

Peptide antigens have been widely used in the development of vaccines, especially for
those against autoimmunity-inducing pathogens and cancers. However, peptide-based …

Most pathogens gain access to the human body and initiate systemic infections through
mucosal sites. A large number of currently marketed licensed vaccines are parenterally …

Peptide based-vaccines are becoming one of the most widely investigated prophylactic and
therapeutic health care interventions against a variety of diseases, including cancer …

Peptide-based vaccines, which form one of the most potent vaccine platforms, offer
exclusive advantages over classical vaccines that use whole organisms or proteins …

Vaccination is a cost-effective approach to prevent, treat, and eradicate infectious diseases
and cancer. Classical whole-organism vaccines may have several pitfalls such as the …