Whole-Genome Sequencing to Predict Mycobacterium tuberculosis Drug Resistance: A Retrospective Observational Study in Eastern China
M Zhang, Y Lu, Y Zhu, K Wu, S Chen, L Zhou, F Wang… - Antibiotics, 2023 - mdpi.com
Pulmonary tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis
(MTB). Whole-genome sequencing (WGS) holds great promise as an advanced technology …
(MTB). Whole-genome sequencing (WGS) holds great promise as an advanced technology …
Exploring Diagnostic Methods for Drug-Resistant Tuberculosis: A Comprehensive Overview
A Sanchini, A Lanni, F Giannoni, A Mustazzolu - Tuberculosis, 2024 - Elsevier
Despite available global efforts and funding, Tuberculosis (TB) continues to affect a
considerable number of patients worldwide. Policy makers and stakeholders set clear goals …
considerable number of patients worldwide. Policy makers and stakeholders set clear goals …
Multidrug-resistant tuberculosis
One of predominant contributors to global mortality is tuberculosis (TB), an infection caused
by Mycobacterium tuberculosis (MTB). Inappropriate and ineffectual treatment can lead to …
by Mycobacterium tuberculosis (MTB). Inappropriate and ineffectual treatment can lead to …
Use of Whole-Genome Sequencing to Predict Mycobacterium tuberculosis Complex Drug Resistance from Early Positive Liquid Cultures
X Wu, G Tan, W Sha, H Liu, J Yang, Y Guo… - Microbiology …, 2022 - Am Soc Microbiol
Our objective was to evaluate the performance of whole-genome sequencing (WGS) from
early positive liquid cultures for predicting Mycobacterium tuberculosis complex (MTBC) …
early positive liquid cultures for predicting Mycobacterium tuberculosis complex (MTBC) …
Analysis of Drug-Resistance Characteristics and Genetic Diversity of Multidrug-Resistant Tuberculosis Based on Whole-Genome Sequencing on the Hainan Island …
J Wang, C Yu, Y Xu, Z Chen, W Qiu… - Infection and Drug …, 2023 - Taylor & Francis
Purpose Given the high burden of Tuberculosis (TB) in China, the prevalence of multidrug-
resistant tuberculosis (MDR-TB) is significant. Whole-genome sequencing (WGS) of …
resistant tuberculosis (MDR-TB) is significant. Whole-genome sequencing (WGS) of …
Drug-Resistant Pulmonary Tuberculosis
O Putri, MA Salim, A Gunawan, D Devin… - Indonesian Journal of …, 2023 - journal.i3l.ac.id
Tuberculosis (TB) caused by the pathogenic bacteria Mycobacterium tuberculosis (MTb) still
remains a highly prevalent disease, particularly in low and middle-income countries. Due to …
remains a highly prevalent disease, particularly in low and middle-income countries. Due to …
Genome sequencing analysis of the pncA, rpsA and panD genes responsible for pyrazinamide resistance of Mycobacterium tuberculosis from Indonesian isolates
Background Developing the most suitable treatment against tuberculosis based on
resistance profiles is imperative to effectively cure tuberculosis patients. Whole‐genome …
resistance profiles is imperative to effectively cure tuberculosis patients. Whole‐genome …
Mutation Detection of Multidrug-Resistant Tuberculosis by RT-PCR Method as the Diagnostic Tool of MDR-TB
S Pambudi - Jurnal Bioteknologi dan Biosains Indonesia, 2023 - ejournal.brin.go.id
Eight percent of tuberculosis (TB) cases worldwide are resistant to rifampicin, with mutations
occurring in the rpoB and katG genes. It is necessary to develop a specific multidrug …
occurring in the rpoB and katG genes. It is necessary to develop a specific multidrug …
The COMBAT-TB Workbench: Making Powerful Mycobacterium tuberculosis Bioinformatics Accessible
Whole-genome sequencing (WGS) is a powerful method for detecting drug resistance,
genetic diversity, and transmission dynamics of Mycobacterium tuberculosis. Implementation …
genetic diversity, and transmission dynamics of Mycobacterium tuberculosis. Implementation …
Phylogenetic lineages of tuberculosis isolates and their association with patient demographics in Tanzania
Background Mycobacterium tuberculosis presents several lineages each with distinct
characteristics of evolutionary status, transmissibility, drug resistance, host interaction …
characteristics of evolutionary status, transmissibility, drug resistance, host interaction …