Glycosylation is a complex co-translational and post-translational modification (PTM) in
eukaryotes that utilizes glycosyltransferases to generate a vast array of glycoconjugate …

A highly critical event in a virus's life cycle is successfully entering a given host. This process
begins when a viral glycoprotein interacts with a target cell receptor, which provides the …

The dense O-glycosylation of mucins plays an important role in the defensive properties of
the mucus hydrogel. Aberrant glycosylation is often correlated with inflammation and …

Glycans are essential to all scales of biology, with their intricate structures being crucial for
their biological functions. The structural complexity of glycans is communicated through …

Glycomics, the comprehensive profiling of all glycan structures in samples, is rapidly
expanding to enable insights into physiology and disease mechanisms. However, glycan …

Glycans possess complex and unique stereochemical features, endowing them with
distinguishing functions. An urgent need to develop a glycan sequencing method to …

Sperm cells are terminally differentiated cells that are essential for reproduction in sexually
reproducing species. Consistent with their highly specialized function, sperm cells harbor a …

Human immunodeficiency virus type 1 (HIV-1) vaccine immunogens capable of inducing
broadly neutralizing antibodies (bNAbs) remain obscure. HIV-1 evades immune responses …

Recent advances in mass spectrometry (MS)-based methods have significantly expanded
the capabilities for quantitative glycoproteomics, enabling highly sensitive and accurate …

Fluorescence labeled glycan homologous mixtures were quantified using fluorescence and
then used to evaluate ionization performances in electrospray ionization at micro, nano, and …