Parkinson's disease (PD) is a neurodegenerative disorder whose aetiology remains unclear:
degeneration involves several neurotransmission systems, resulting in a heterogeneous …

With the advancement of systems biology research, we have already seen great progress in
pharmacology studies, especially in network pharmacology. Network pharmacology has …

YKL-40 is a 40 kDa glycoprotein produced by cancer cells, inflammatory cells and stem
cells. It probably has a role in cell proliferation and differentiation, inflammation, protection …

Background Epigenetic variation has been linked to several human diseases. Proliferative
diabetic retinopathy (PDR) is a major cause of vision loss in subjects with diabetes …

Age-related cognitive decline occurs without frank neurodegeneration and is the most
common cause of memory impairment in aging individuals. With increasing longevity …

Diabetic retinopathy (DR) is the leading cause of blindness in working-age adults. Early
stage DR involves inflammation, vascular leakage, apoptosis of vascular cells and …

Background Recently, interferon-inducible guanylate binding protein (GBP2) has been
discussed as a possible control factor in tumor development, which is controlled by p53, and …

Diabetic retinopathy was included by the World Health Organization in the eye disease
priority list. Up to now, only proliferative diabetic retinopathy can be treated with approved …

Diabetes pathology derives from the combination of hyperglycemia and hypoinsulinemia or
insulin resistance leading to diabetic complications including diabetic neuropathy …

Purpose: This study evaluated if tauroursodeoxycholic acid (TUDCA) alleviates pro-
inflammatory and endoplasmic reticulum (ER) stress-mediated visual deficits in diabetic tie2 …