Obstructive sleep apnea: current perspectives

AM Osman, SG Carter, JC Carberry… - Nature and science of …, 2018 - Taylor & Francis
The prevalence of obstructive sleep apnea (OSA) continues to rise. So too do the health,
safety, and economic consequences. On an individual level, the causes and consequences …

Phenotypic approaches to obstructive sleep apnoea–new pathways for targeted therapy

DJ Eckert - Sleep medicine reviews, 2018 - Elsevier
People develop obstructive sleep apnoea (OSA) for different reasons. The ability to
understand these reasons, easily identify them in individual patients, and develop therapies …

Adult obstructive sleep apnoea

AS Jordan, DG McSharry, A Malhotra - The Lancet, 2014 - thelancet.com
Obstructive sleep apnoea is an increasingly common disorder of repeated upper airway
collapse during sleep, leading to oxygen desaturation and disrupted sleep. Features include …

Upper-airway stimulation for obstructive sleep apnea

PJ Strollo Jr, RJ Soose, JT Maurer… - … England Journal of …, 2014 - Mass Medical Soc
Background Obstructive sleep apnea is associated with considerable health risks. Although
continuous positive airway pressure (CPAP) can mitigate these risks, effectiveness can be …

Defining phenotypic causes of obstructive sleep apnea. Identification of novel therapeutic targets

DJ Eckert, DP White, AS Jordan, A Malhotra… - American journal of …, 2013 - atsjournals.org
Rationale: The pathophysiologic causes of obstructive sleep apnea (OSA) likely vary among
patients but have not been well characterized. Objectives: To define carefully the proportion …

Personalized management approach for OSA

JC Carberry, J Amatoury, DJ Eckert - Chest, 2018 - Elsevier
OSA is a heterogeneous disorder. If left untreated, it has major health, safety, and economic
consequences. In addition to varying levels of impairment in pharyngeal anatomy …

Clinical consequences and economic costs of untreated obstructive sleep apnea syndrome

M Knauert, S Naik, MB Gillespie… - World Journal of …, 2015 - mednexus.org
Objective: To provide an overview of the healthcare and societal consequences and costs of
untreated obstructive sleep apnea syndrome. Data sources: PubMed database for English …

Three-year outcomes of cranial nerve stimulation for obstructive sleep apnea: the STAR trial

BT Woodson, RJ Soose, MB Gillespie… - … --head and neck …, 2016 - journals.sagepub.com
Objective To describe the 36-month clinical and polysomnography (PSG) outcomes in an
obstructive sleep apnea (OSA) cohort treated with hypoglossal cranial nerve upper airway …

Evaluation of drug-induced sleep endoscopy as a patient selection tool for implanted upper airway stimulation for obstructive sleep apnea

OM Vanderveken, JT Maurer, W Hohenhorst… - Journal of clinical …, 2013 - jcsm.aasm.org
Study Objectives: To study the possible predictive value of drug-induced sleep endoscopy
(DISE) in assessing therapeutic response to implanted upper airway stimulation (UAS) for …

Hypoglossal nerve stimulation long-term clinical outcomes: a systematic review and meta-analysis

A Costantino, V Rinaldi, A Moffa, V Luccarelli… - Sleep and …, 2020 - Springer
Objective To perform a systematic review and meta-analysis for studies evaluating
hypoglossal nerve stimulation (HNS) clinical outcomes in the treatment of moderate to …