Macrophages are present in most human tissues and have very diverse functions. Activated
macrophages are usually divided into two phenotypes, M1 macrophages and M2 …

Tuberculosis (TB) is a serious global public health challenge that results in significant
morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium …

Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, an infectious
disease with one of the highest morbidity and mortality rates worldwide. Leveraging its …

Infectious diseases caused by pathogens including viruses, bacteria, fungi, and parasites
are ranked as the second leading cause of death worldwide by the World Health …

The inflammasome-mediated cleavage of gasdermin D (GSDMD) causes pyroptosis and
inflammatory cytokine release to control pathogen infection, but how pathogens evade this …

Phagocytosis is a fundamental process of cells to capture and ingest foreign particles. Small
unicellular organisms such as free-living amoeba use this process to acquire food. In …

Mycobacterium tuberculosis (Mtb), the etiological agent of human tuberculosis (TB), has
plagued humans for thousands of years. TB still remains a major public health problem in …

Phosphoinositides (PIs) make up only a small fraction of cellular phospholipids, yet they
control almost all aspects of a cell's life and death. These lipids gained tremendous research …

The Mycobacterium tuberculosis complex (MTBC) consists of closely related species that
cause tuberculosis in both humans and animals. This illness, still today, remains to be one of …

Tuberculosis (TB) remains a major health threat, killing nearly 2 million individuals around
this globe, annually. The only vaccine, developed almost a century ago, provides limited …