Interest in BDNF as an activity-dependent modulator of neuronal structure and function in
the adult brain has intensified in recent years. Localization of BDNF-TrkB to glutamate …

The proteins of the mammalian neurotrophin family (nerve growth factor (NGF), brain-
derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) and neurotrophin-4/5 (NT-4/5)) …

Brain-derived neurotrophic factor (BDNF) plays a critical role in activity-dependent
modifications of neuronal connectivity and synaptic strength, including establishment of …

To define activity-dependent release of endogenous brain-derived neurotrophic factor
(BDNF), we developed an in vitro model using primary sensory neurons and a modified …

The ever-unfolding biology of NGF is consistent with a target-derived retrograde mode of
action in peripheral and central neurons. However, another member of the neurotrophin …

Neurotrophins play an important role in modulating activity-dependent neuronal plasticity. In
particular, threshold levels of brain-derived neurotrophic factor (BDNF) are required to …

The mammalian neurotrophins (NTs) NGF, BDNF, NT-3, and NT-4 constitute a family of
secreted neuronal growth factors. In addition, NTs are implicated in several forms of activity …

In addition to the known retrograde transport of neurotrophins, it is now evident that
endogenous brain-derived neurotrophic factor (BDNF) is transported in the anterograde …

The nervous system plays a central role in regulating the stem cell niche in many organs,
and thereby pivotally modulates development, homeostasis, and plasticity. A similarly …

Both antidepressant treatment and physical exercise have been shown to increase
circulating levels of norepinephine (NE) and hippocampal brain-derived neurotrophic factor …