The mechanical role of the cervix in pregnancy

KM Myers, H Feltovich, E Mazza, J Vink, M Bajka… - Journal of …, 2015 - Elsevier
Appropriate mechanical function of the uterine cervix is critical for maintaining a pregnancy
to term so that the fetus can develop fully. At the end of pregnancy, however, the cervix must …

Cervical etiology of spontaneous preterm birth

J Vink, H Feltovich - Seminars in Fetal and Neonatal Medicine, 2016 - Elsevier
The cervix functions as a barrier between the uterus and vagina and keeps the uterus closed
until term so that the fetus can develop. For delivery the cervix must soften and dilate, and …

Uterocervical angle: a novel ultrasound screening tool to predict spontaneous preterm birth

M Dziadosz, TA Bennett, C Dolin, AW Honart… - American journal of …, 2016 - Elsevier
Background Mechanical alteration of the cervical angle has been proposed to reduce
spontaneous preterm birth. Performance of the uterocervical angle as measured by …

A new paradigm for the role of smooth muscle cells in the human cervix

JY Vink, S Qin, CO Brock, NM Zork, HM Feltovich… - American journal of …, 2016 - Elsevier
Background Premature cervical remodeling resulting in spontaneous preterm birth may
begin with premature failure or relaxation at the internal os (termed “funneling”). To date, we …

Immunobiology of cervix ripening

SM Yellon - Frontiers in Immunology, 2020 - frontiersin.org
The cervix is the essential gatekeeper for birth. Incomplete cervix remodeling contributes to
problems with delivery at or post-term while preterm birth is a major factor in perinatal …

Mechanics of cervical remodelling: insights from rodent models of pregnancy

K Yoshida, C Jayyosi, N Lee… - Interface …, 2019 - royalsocietypublishing.org
The uterine cervix undergoes a complex remodelling process during pregnancy,
characterized by dramatic changes in both extracellular matrix (ECM) structure and …

Collagen fiber orientation and dispersion in the upper cervix of non-pregnant and pregnant women

W Yao, Y Gan, KM Myers, JY Vink, RJ Wapner… - PloS one, 2016 - journals.plos.org
The structural integrity of the cervix in pregnancy is necessary for carrying a pregnancy until
term, and the organization of human cervical tissue collagen likely plays an important role in …

Auto-detection of cervical collagen and elastin in Mueller matrix polarimetry microscopic images using K-NN and semantic segmentation classification

C Roa, VN Du Le, M Mahendroo… - Biomedical Optics …, 2021 - opg.optica.org
We propose an approach for discriminating fibrillar collagen fibers from elastic fibers in the
mouse cervix in Mueller matrix microscopy using convolutional neural networks (CNN) and …

Fetal membranes, not a mere appendage of the placenta, but a critical part of the fetal-maternal interface controlling parturition

R Menon, JJ Moore - Obstetrics and Gynecology Clinics, 2020 - obgyn.theclinics.com
Obstetricians, neonatologists, and reproductive scientists have collectively performed much
research in pregnancy and parturition. These authors contend, however, that a major …

Biomechanics of the human uterus

KM Myers, D Elad - Wiley Interdisciplinary Reviews: Systems …, 2017 - Wiley Online Library
The appropriate biomechanical function of the uterus is required for the execution of human
reproduction. These functions range from aiding the transport of the embryo to the …