Prenylated isoflavonoids from plants as selective estrogen receptor modulators (phytoSERMs)

R Simons, H Gruppen, TFH Bovee, MA Verbruggen… - Food & function, 2012 - pubs.rsc.org
Isoflavonoids are a class of secondary metabolites, which comprise amongst others the
subclasses of isoflavones, isoflavans, pterocarpans and coumestans. Isoflavonoids are …

The flavanone naringenin reduces the production of quorum sensing-controlled virulence factors in Pseudomonas aeruginosa PAO1

OM Vandeputte, M Kiendrebeogo… - …, 2011 - microbiologyresearch.org
Preliminary screening of the Malagasy plant Combretum albiflorum for compounds
attenuating the production of quorum sensing (QS)-controlled virulence factors in bacteria …

Natural estrogen receptor modulators and their heterologous biosynthesis

J Yang, L Wen, Y Jiang, B Yang - Trends in Endocrinology & Metabolism, 2019 - cell.com
Estrogen receptors (ERs) are transcription factors highly involved in physiological
development and metabolism in the human body. They also play important roles in the …

Isoflavone intake and the risk of coronary heart disease in US men and women: results from 3 prospective cohort studies

L Ma, G Liu, M Ding, G Zong, FB Hu, WC Willett… - Circulation, 2020 - Am Heart Assoc
Background: Whether soy products confer health benefits related to coronary heart disease
(CHD) remains controversial because of inconsistent evidence. Methods: A total of 74 241 …

Anti-inflammatory role of the isoflavone diadzein in lipopolysaccharide-stimulated microglia: implications for Parkinson's disease

SJ Chinta, A Ganesan, P Reis-Rodrigues… - Neurotoxicity …, 2013 - Springer
Microglial activation and subsequent release of toxic pro-inflammatory factors are believed
to play an important role in neuronal cell death associated with Parkinson's disease (PD) …

The Suzuki–Miyaura Cross-Coupling–Claisen Rearrangement–Cross-Metathesis Approach to Prenylated Isoflavones

G Kwesiga, J Greese, A Kelling… - The Journal of …, 2023 - ACS Publications
Isoflavones were synthesized via Suzuki–Miyaura coupling of 3-iodochromones and para-
methoxybenzene-and para-phenolboronic acid. In our hands, conditions commonly used for …

High-performance polyimides derived from biomass: design, synthesis, and properties

C Gong, Z Liu, Z Tao, A Xu, H Xie, Q Fang… - ACS Sustainable …, 2023 - ACS Publications
The development of sustainable polyimides (PIs) from abundant renewable biogenic
feedstocks has been limited by the bio-based content and the lack of mechanical and …

Dietary phytoestrogens and total and cause-specific mortality: results from 2 prospective cohort studies

Z Chen, F Qian, Y Hu, T Voortman, Y Li… - The American Journal of …, 2023 - Elsevier
Background Evidence regarding dietary phytoestrogens in relation to mortality remains
limited. Objectives The objective of the study is to examine the associations of intake of …

The soybean high density 'Forrest'by 'Williams 82'SNP-based genetic linkage map identifies QTL and candidate genes for seed isoflavone content

D Knizia, J Yuan, N Bellaloui, T Vuong, M Usovsky… - Plants, 2021 - mdpi.com
Isoflavones are secondary metabolites that are abundant in soybean and other legume
seeds providing health and nutrition benefits for both humans and animals. The objectives of …

Potentials of natural antioxidants from plants as antiosteoporotic agents

E Sakai, F Farhana, Y Yamaguchi, T Tsukuba - Studies in Natural Products …, 2022 - Elsevier
In osteoporosis, the density and quality of bone are reduced and become more fragile, with
a significantly increased risk of fracture. Living tissue of bone undergoes continuous …