The monovalent methyl group is derived from methane through the removal of a hydrogen
atom, 1 and its etymology is directly related to the discovery of methanol. 2 The first reports …

An underlying goal of drug discovery is to develop safe and stable substances that
specifically target essential elements that cause disease. Molecular chirality adds an …

An NHC-catalyzed atroposelective reaction between ynals and urazoles is disclosed. The
reaction establishes a chiral C–N axis via an atroposelective [3+ 2] annulation …

In economic terms, biodiversity transcends the boundaries usually given to conventional
industries because it is a valuable source of biological and chemical data of great use to …

This review demonstrates the importance of plants as sources of molecules used in
anticancer therapies. The approach is performed by relating the active molecules to their …

This minireview covers the literature of the last decade related to the stereochemistry of
axially chiral molecules. The first section reviews the use of dynamic NMR and dynamic …

Abstract BACKGROUND Potato virus Y (PVY) was first discovered by Smith in 1931 and is
currently ranked as the fifth most significant plant virus. It can cause severe damage to plants …

The main aspects of the modern Medicinal Chemistry, among the classic and industrial
paradigms, used in the drug discovery process will be treated. The contribution of the …

Nine bis-9, 10-dihydrophenanthrene and 9, 10-dihydrophenanthrene/(dihydro) stilbene
derivatives, including the new phochinenins GL 1–6, were isolated from the whole plant of …

The stereodynamic behavior of a series of pyrazolo [3, 4-b] pyridines was studied. The
restricted rotations of the aryl substituent in position 4 of the heteroaromatic ring and of the …