Low molecular weight thiol-containing compounds have an essential role in many
biochemical and pharmacological reactions due to the ease with each they are oxidized …

Recent evidence is reviewed indicating increased oxidative damage in Type 1 and Type 2
diabetes mellitus as well as deficits in antioxidant defence enzymes and vitamins …

An increasing body of evidence from animal models, human specimens and cell lines points
to reactive oxygen species as likely involved in the pathways, which convey both …

Cells in the renal inner medulla are normally exposed to extraordinarily high levels of NaCl
and urea. The osmotic stress causes numerous perturbations because of the hypertonic …

Aldose reductase (AR) is widely expressed aldehyde-metabolizing enzyme. The reduction
of glucose by the AR-catalyzed polyol pathway has been linked to the development of …

Background—A significant number of patients treated with anthracyclines develop
cardiotoxicity (anthracycline-induced cardiotoxicity [ACT]), mainly presenting as arrhythmias …

The mechanisms of thiol metabolism and chemistry have particular relevance to both
cellular defenses against toxicant exposure and to redox signaling. Here, we will focus on …

A comprehensive focus on 4‐hydroxynonenal (HNE) as candidate molecule in a variety of
pathophysiological conditions occurring in humans is here provided. Despite an active, now …

Aldose reductase and the roBackgroundphropathy. Background In diabetic renal
complications, hyperglycemia may cause damage at a cellular level in both glomerular and …

The changes in gene expression underlying the yeast adaptive stress response to H 2 O 2
were analyzed by comparative two-dimensional gel electrophoresis of total cell proteins …