Highlights (AQPs) are transmembrane proteins responsible for fast water movement across
cell membranes, including those of astrocytes. The expression and subcellular localization …

Since the discovery of aquaporins, it has become clear that the various mammalian
aquaporins play critical physiological roles in water and ion balance in multiple tissues …

Stress and glucocorticoid hormones regulate hippocampal neurogenesis, but the molecular
mechanisms underlying their effects are unknown. We, therefore, investigated the molecular …

BACKGROUND: Depression and cerebrovascular disease influence each other, according
to clinical studies. Despite this evidence, no studies have investigated the relationship …

Aquaporin-4 (AQP4) is the predominant water channel expressed by astrocytes in the
central nervous system (CNS). AQP4 is widely expressed throughout the brain, especially at …

Traumatic brain injury (TBI) is one of the leading causes of death and disability in children
and adolescents. The neuropathological sequelae that result from TBI are a complex …

Aquaporin-4 (AQP4) channels play an important role in brain water homeostasis. Water
transport across plasma membranes has a critical role in brain water exchange of the …

The aim of this article is to describe the roles of water channel proteins (WCPs) in brain
functionality. The fluid compartments of the brain, which include the brain parenchyma (with …

In the adult brain, the water channel aquaporin‐4 (AQP4) is expressed in astrocyte endfoot,
in supramolecular assemblies, called “Orthogonal Arrays of Particles”(OAPs) together with …

Neural stem cells (NSCs) in the adult murine subependymal zone balance their self-renewal
capacity and glial identity with the potential to generate neurons during the lifetime. Adult …