Hypertension affects approximately one third of the world's adult population and is a major
cause of premature death despite considerable advances in pharmacological treatments …

Background Purpose: to establish if exercise training improves clinical outcomes in people
with metabolic syndrome (MetS). Registered with PROSPERO international prospective …

Sympathetic tone is well recognised as being implicit in cardiovascular control. It is less
readily acknowledged that activation of the sympathetic nervous system is integral in energy …

Hypertension is a global public health issue and the leading cause of premature death in
humans. Despite more than a century of research, hypertension remains difficult to cure due …

Background and aims Exercise is beneficial to individuals with metabolic syndrome (MetS).
An understudied group, who represent the majority of the MetS population, are individuals …

The effects of exercise training (Ex), dietary interventions (DIs), and a combination of Ex and
DI (Ex+ DI) on leptin and adiponectin have been established. However, less is known …

Arterial hypertension is strongly related to overweight and obesity. In obese subjects,
several mechanisms may lead to hypertension such as insulin and leptin resistance …

Effective strategies are required to reduce the prevalence of overweight and obesity;
however, the effectiveness of current weight loss programmes is variable. One contributing …

A neurogenic component to primary hypertension (hypertension) is now well established.
Along with raised vasomotor tone and increased cardiac output, the chronic activation of the …

The world wide prevalence of obesity and the metabolic syndrome is escalating. Contrary to
earlier experimental evidence, human obesity is characterised by sympathetic nervous …