Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy
TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical Reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Ferroptosis in cancer and cancer immunotherapy
The hallmark of tumorigenesis is the successful circumvention of cell death regulation for
achieving unlimited replication and immortality. Ferroptosis is a newly identified type of cell …
achieving unlimited replication and immortality. Ferroptosis is a newly identified type of cell …
Engineering nanomedicine for glutathione depletion-augmented cancer therapy
Y Xiong, C Xiao, Z Li, X Yang - Chemical Society Reviews, 2021 - pubs.rsc.org
Glutathione (GSH), the main redox buffer, has long been recognized as a pivotal modulator
of tumor initiation, progression and metastasis. It is also implicated in the resistance of …
of tumor initiation, progression and metastasis. It is also implicated in the resistance of …
Polyphenol‐containing nanoparticles: synthesis, properties, and therapeutic delivery
Polyphenols, the phenolic hydroxyl group‐containing organic molecules, are widely found in
natural plants and have shown beneficial effects on human health. Recently, polyphenol …
natural plants and have shown beneficial effects on human health. Recently, polyphenol …
Supramolecular cancer nanotheranostics
Among the many challenges in medicine, the treatment and cure of cancer remains an
outstanding goal given the complexity and diversity of the disease. Nanotheranostics, the …
outstanding goal given the complexity and diversity of the disease. Nanotheranostics, the …
Stimuli‐responsive manganese single‐atom nanozyme for tumor therapy via integrated cascade reactions
The single‐atom enzyme (SAE) is a novel type of nanozyme that exhibits extraordinary
catalytic activity. Here, we constructed a PEGylated manganese‐based SAE (Mn/PSAE) by …
catalytic activity. Here, we constructed a PEGylated manganese‐based SAE (Mn/PSAE) by …
Recent advances in nanomaterial‐based nanoplatforms for chemodynamic cancer therapy
SL Li, P Jiang, FL Jiang, Y Liu - Advanced Functional Materials, 2021 - Wiley Online Library
Triggered by the endogenous chemical energy in the tumor microenvironment (TME),
chemodynamic therapy (CDT) as an emerging non‐exogenous stimulant therapeutic …
chemodynamic therapy (CDT) as an emerging non‐exogenous stimulant therapeutic …
[HTML][HTML] Recent advances of cancer chemodynamic therapy based on Fenton/Fenton-like chemistry
C Cao, X Wang, N Yang, X Song, X Dong - Chemical Science, 2022 - pubs.rsc.org
Applying Fenton chemistry in the tumor microenvironment (TME) for cancer therapy is the
most significant feature of chemodynamic therapy (CDT). Owing to the mild acid and …
most significant feature of chemodynamic therapy (CDT). Owing to the mild acid and …
Metallodrugs in cancer nanomedicine
Metal complexes are extensively used for cancer therapy. The multiple variables available
for tuning (metal, ligand, and metal–ligand interaction) offer unique opportunities for drug …
for tuning (metal, ligand, and metal–ligand interaction) offer unique opportunities for drug …
Peroxidase-like active nanomedicine with dual glutathione depletion property to restore oxaliplatin chemosensitivity and promote programmed cell death
F Wu, Y Du, J Yang, B Shao, Z Mi, Y Yao, Y Cui, F He… - ACS …, 2022 - ACS Publications
The nanocatalytic activity of nanozymes provides a vision for tumor treatment. However, the
glutathione (GSH)-related antioxidant defense system (ADS) formed on the basis of …
glutathione (GSH)-related antioxidant defense system (ADS) formed on the basis of …