Most nerves are attached to the neuraxis by rootlets. The CNS–PNS transitional zone (TZ) is
that length of rootlet containing both central and peripheral nervous tissue. The 2 tissues are …

Lesions to the nervous system often produce hemorrhage and tissue loss that are difficult, if
not impossible, to repair. Therefore, scar formation, inflammation and cavitation take place …

Avulsion of nerve roots from the spinal cord is widely regarded as an untreatable injury.
However, a series of experiments in animals has shown that, if continuity is restored …

Seventy-eight patients who had a complete brachial plexus palsy caused by a stretching
injury were operated on by the same surgeon between January 1980 and December 1991 …

Failure of axonal regeneration in the central nervous system (CNS) is mainly attributed to a
lack of intrinsic neuronal growth programs and an inhibitory environment from a glial scar …

Object. The authors review the first series of 10 cases in which injured intraspinal brachial
plexus were surgically repaired. They describe the technique of spinal cord implantation or …

A spinal root avulsion is the most severe proximal peripheral nerve lesion possible. Avulsion
of ventral root filaments disconnects spinal motoneurons from their target muscles, resulting …

Unilateral avulsion of lumbar ventral roots kills approximately 50% of injured motoneurons
within 2 weeks of surgery. Immediate treatment involving surgical reimplantation of the …

Background Ventral root avulsion is an experimental model of proximal axonal injury at the
central/peripheral nervous system interface that results in paralysis and poor clinical …

Activating transcription factor 3 (ATF3) is induced in various tissues in response to stress. In
this experiment, ATF3 expression was studied in adult rats subjected either to a dorsal or …