Less label, more free: approaches in label‐free quantitative mass spectrometry
In this review we examine techniques, software, and statistical analyses used in label‐free
quantitative proteomics studies for area under the curve and spectral counting approaches …
quantitative proteomics studies for area under the curve and spectral counting approaches …
Global and site‐specific analysis of protein glycosylation in complex biological systems with Mass Spectrometry
H Xiao, F Sun, S Suttapitugsakul… - Mass spectrometry …, 2019 - Wiley Online Library
Protein glycosylation is ubiquitous in biological systems and plays essential roles in many
cellular events. Global and site‐specific analysis of glycoproteins in complex biological …
cellular events. Global and site‐specific analysis of glycoproteins in complex biological …
Structural analysis of N-and O-glycans released from glycoproteins
This protocol shows how to obtain a detailed glycan compositional and structural profile from
purified glycoproteins or protein mixtures, and it can be used to distinguish different isobaric …
purified glycoproteins or protein mixtures, and it can be used to distinguish different isobaric …
DNA methylome and transcriptome alterations and cancer prevention by curcumin in colitis-accelerated colon cancer in mice
Inflammation is highly associated with colon carcinogenesis. Epigenetic mechanisms could
play an important role in the initiation and progression of colon cancer. Curcumin, a dietary …
play an important role in the initiation and progression of colon cancer. Curcumin, a dietary …
Heparan sulfate proteoglycan signaling in tumor microenvironment
V De Pasquale, LM Pavone - International Journal of Molecular Sciences, 2020 - mdpi.com
In the last few decades, heparan sulfate (HS) proteoglycans (HSPGs) have been an
intriguing subject of study for their complex structural characteristics, their finely regulated …
intriguing subject of study for their complex structural characteristics, their finely regulated …
Comparative structural analysis of the glycosylation of salivary and buccal cell proteins: innate protection against infection by Candida albicans
Mucosal epithelial surfaces, such as line the oral cavity, are common sites of microbial
colonization by bacteria, yeast and fungi. The microbial interactions involve adherence …
colonization by bacteria, yeast and fungi. The microbial interactions involve adherence …
Glycomics and glycoproteomics of membrane proteins and cell‐surface receptors: Present trends and future opportunities
KB Chandler, CE Costello - Electrophoresis, 2016 - Wiley Online Library
Membrane proteins mediate cell–cell interactions and adhesion, the transfer of ions and
metabolites, and the transmission of signals from the extracellular environment to the cell …
metabolites, and the transmission of signals from the extracellular environment to the cell …
NEGATIVE ION MASS SPECTROMETRY FOR THE ANALYSIS OF N‐LINKED GLYCANS
DJ Harvey - Mass Spectrometry Reviews, 2020 - Wiley Online Library
N‐glycans from glycoproteins are complex, branched structures whose structural
determination presents many analytical problems. Mass spectrometry, usually conducted in …
determination presents many analytical problems. Mass spectrometry, usually conducted in …
Structural analysis of glycoprotein sialylation–part II: LC-MS based detection
Structural characterisation of sialylated glycoproteins in time and space is a requirement for
further understanding of their involvement in biology. In this second of two related reviews …
further understanding of their involvement in biology. In this second of two related reviews …
Relative quantification of N-glycopeptide sialic acid linkage isomers by ion mobility mass spectrometry
X Feng, H Shu, S Zhang, Y Peng, L Zhang… - Analytical …, 2021 - ACS Publications
Sialic acids decorate the surface of glycoproteins and play important roles in a variety of
pathological processes. Although the mass spectrometry (MS) based linkage-specific …
pathological processes. Although the mass spectrometry (MS) based linkage-specific …