Haloperidol‐induced catalepsy as an animal model for parkinsonism: A systematic review of experimental studies
I Waku, MS Magalhaes, CO Alves… - European Journal of …, 2021 - Wiley Online Library
Several useful animal models for parkinsonism have been developed so far. Haloperidol‐
induced catalepsy is often used as a rodent model for the study of motor impairments …
induced catalepsy is often used as a rodent model for the study of motor impairments …
Targeted activation of midbrain neurons restores locomotor function in mouse models of parkinsonism
D Masini, O Kiehn - Nature communications, 2022 - nature.com
The pedunculopontine nucleus (PPN) is a locomotor command area containing
glutamatergic neurons that control locomotor initiation and maintenance. These motor …
glutamatergic neurons that control locomotor initiation and maintenance. These motor …
Paradoxical kinesia may no longer be a paradox waiting for 100 years to be unraveled
L Melo-Thomas, RKW Schwarting - Reviews in the Neurosciences, 2023 - degruyter.com
Parkinson's disease (PD) is a progressive neurodegenerative disorder mainly characterized
by bradykinesia and akinesia. Interestingly, these motor disabilities can depend on the …
by bradykinesia and akinesia. Interestingly, these motor disabilities can depend on the …
Lipid nanocarrier of selegiline augmented anti-Parkinson's effect via P-gp modulation using quercetin
In the present study, SEL was loaded in a lipid nanocarrier (LNC) formulation with a P-gp
pump inhibitor ie, Quercetin (QUR) for improving the bioavailability of the SEL in the brain …
pump inhibitor ie, Quercetin (QUR) for improving the bioavailability of the SEL in the brain …
In vivo Probabilistic Structural Atlas of the Inferior and Superior Colliculi, Medial and Lateral Geniculate Nuclei and Superior Olivary Complex in Humans Based on 7 …
MG García-Gomar, C Strong, N Toschi… - Frontiers in …, 2019 - frontiersin.org
Despite extensive neuroimaging research of primary sensory cortices involved in auditory
and visual functions, subcortical structures within these domains, such as the inferior and …
and visual functions, subcortical structures within these domains, such as the inferior and …
Cortical neurostimulation and N-methyl-D-aspartate glutamatergic receptor activation in the dysgranular layer of the posterior insular cortex modulate chronic …
RCM Pereira, P Medeiros, NC Coimbra… - … : Technology at the …, 2023 - Elsevier
Abstract Background and Aims The dysgranula parts of the posterior insular cortex (PIC)
stimulation (PICS) has been investigated as a new putative cortical target for …
stimulation (PICS) has been investigated as a new putative cortical target for …
Deep cerebellar stimulation reduces ataxic motor symptoms in the shaker rat
Objective Degenerative cerebellar ataxias (DCAs) affect up to 1 in 5,000 people worldwide,
leading to incoordination, tremor, and falls. Loss of Purkinje cells, nearly universal across …
leading to incoordination, tremor, and falls. Loss of Purkinje cells, nearly universal across …
Predictive accuracy of CNN for cortical oscillatory activity in an acute rat model of parkinsonism
In neurological and neuropsychiatric disorders neuronal oscillatory activity between basal
ganglia and cortical circuits are altered, which may be useful as biomarker for adaptive deep …
ganglia and cortical circuits are altered, which may be useful as biomarker for adaptive deep …
Low frequency deep brain stimulation in the inferior colliculus ameliorates haloperidol-induced catalepsy and reduces anxiety in rats
H Ihme, RKW Schwarting, L Melo-Thomas - PLoS One, 2020 - journals.plos.org
Deep brain stimulation (DBS) of the colliculus inferior (IC) improves haloperidol-induced
catalepsy and induces paradoxal kinesia in rats. Since the IC is part of the brain aversive …
catalepsy and induces paradoxal kinesia in rats. Since the IC is part of the brain aversive …
Lateralization in Hemiparkinsonian Rats Is Affected by either Deep Brain Stimulation or Glutamatergic Neurotransmission in the Inferior Colliculus
L Melo-Thomas, L Tacken, N Richter, D de Almeida… - Eneuro, 2022 - eneuro.org
After unilateral lesion of the medial forebrain bundle by 6-OHDA rats exhibit lateralized
deficits in spontaneous behavior or apomorphine-induced rotations. We investigated …
deficits in spontaneous behavior or apomorphine-induced rotations. We investigated …