This review focuses on neuropeptides and peptide hormones, the largest and most diverse
class of neuroactive substances, known in Drosophila and other animals to play roles in …

Organisms adapt to changing environments by adjusting their development, metabolism,
and behavior to improve their chances of survival and reproduction. To achieve such …

Animals must adapt their dietary choices to meet their nutritional needs. How these needs
are detected and translated into nutrient-specific appetites that drive food-choice behaviours …

A balanced intake of macronutrients—protein, carbohydrate and fat—is essential for the well-
being of organisms. An adequate calorific intake but with insufficient protein consumption …

The circadian clock and its output pathways play a pivotal role in optimizing daily processes.
To obtain insights into how diverse rhythmic physiology and behaviors are orchestrated, we …

Mechanistic target of rapamycin complex 1 (mTORC1) regulates cell growth and metabolism
in response to multiple nutrients, including the essential amino acid leucine. Recent work in …

Genetic approaches in the fruit fly, Drosophila melanogaster, have led to a major triumph in
the field of sensory biology—the discovery of multiple large families of sensory receptors …

Plasticity in animal behaviour relies on the ability to integrate external and internal cues from
the changing environment and hence modulate activity in synaptic circuits of the brain. This …

The insect gustatory system senses taste information from environmental food substrates
and processes it to control feeding behaviors. Drosophila melanogaster has been a …

Obesity imposes a global health threat and calls for safe and effective therapeutic options.
Here, we found that protein-rich diet significantly reduced body fat storage in fruit flies, which …