Biocatalytic gateway to convert glycerol into 3-hydroxypropionic acid in waste-based biorefineries: Fundamentals, limitations, and potential research strategies

HM Zabed, S Akter, PF Rupani, J Akor, Y Zhang… - Biotechnology …, 2023 - Elsevier
Microbial conversion of bioenergy-derived waste glycerol into value-added chemicals has
emerged as an important bioprocessing technology due to its eco-friendliness, feasible …

Production of 3-hydroxypropionic acid from renewable substrates by metabolically engineered microorganisms: a review

X Wang, Z Cui, X Sun, Z Wang, T Chen - Molecules, 2023 - mdpi.com
3-Hydroxypropionic acid (3-HP) is a platform chemical with a wide range of existing and
potential applications, including the production of poly (3-hydroxypropionate)(P-3HP), a …

Recent advances in metabolic engineering of microorganisms for the production of monomeric C3 and C4 chemical compounds

S Zhou, Y Zhang, Z Wei, S Park - Bioresource Technology, 2023 - Elsevier
Bio-based C3 and C4 bi-functional chemicals are useful monomers in biopolymer
production. This review describes recent progresses in the biosynthesis of four such …

Biosynthesis pathways and strategies for improving 3-hydroxypropionic acid production in bacteria

P Zhao, P Tian - World Journal of Microbiology and Biotechnology, 2021 - Springer
Hydroxypropionic acid (3-HP) represents an economically important platform compound
from which a panel of bulk chemicals can be derived. Compared with petroleum-dependent …

Multiplex modification of Escherichia coli for enhanced β-alanine biosynthesis through metabolic engineering

P Wang, HY Zhou, B Li, WQ Ding, ZQ Liu… - Bioresource …, 2021 - Elsevier
Abstract β-Alanine is the only naturally occurring β-amino acid, widely used in the fine
chemical and pharmaceutical fields. In this study, metabolic design strategies were …

Antibacterial and anti-biofilm efficacy of selenium nanoparticles against Pseudomonas aeruginosa: Characterization and in vitro analysis

C Thamayandhi, MA El-Tayeb, SRM Syed… - Microbial …, 2024 - Elsevier
Abstract Pseudomonas aeruginosa (P. aeruginosa), a Gram-negative opportunistic
pathogen, poses significant treatment challenges due to its antibiotic resistance and biofilm …

Time-dependent numerical investigation of 3-hydroxypropionic acid extraction using a microporous membrane contactor

Y Cao, AT Nakhjiri, SM Sarkar, M Ghadiri - The European Physical …, 2022 - Springer
Extraction process of acidic materials inside the microporous membrane contactors has
been an interesting subject all over the world. In this paper, a novel time-dependent two …

Trends in valorization of highly-toxic lignocellulosic biomass derived-compounds via engineered microbes

LN Jayakody, B Chinmoy, TL Turner - Bioresource Technology, 2022 - Elsevier
Lignocellulosic biomass-derived fuels, chemicals, and materials are promising sustainable
solutions to replace the current petroleum-based production. The direct microbial conversion …

Improvement of 3-hydroxypropionic acid tolerance in Klebsiella pneumoniae by novel transporter YohJK

TP Nguyen-Vo, H Ryu, M Sauer, S Park - Bioresource Technology, 2022 - Elsevier
Hydroxypropionic acid (3-HP) is a platform chemical which has potential applications in
cosmetic and polymer industries. Microbial production of 3-HP is hampered by its toxic effect …

Engineering of the Substrate Pocket of α-ketoglutaric Semialdehyde Dehydrogenase for Improving the Activity toward 3-hydroxypropanal

YS Park, A Nasir, TP Nguyen-Vo, H Ryu… - Biotechnology and …, 2023 - Springer
Hydroxypropionic acid (3-HP) is a key building block for value-added chemicals. A
biological route for synthesizing this molecule is two-step enzymatic reactions; dehydration …