An insight into the recent development of the clinical candidates for the treatment of malaria and their target proteins

H Madhav, N Hoda - European Journal of Medicinal Chemistry, 2021 - Elsevier
Malaria is an endemic disease, prevalent in tropical and subtropical regions which cost half
of million deaths annually. The eradication of malaria is one of the global health priority …

Heterocyclic compounds bearing triazine scaffold and their biological significance: A review

T Verma, M Sinha, N Bansal - Anti-Cancer Agents in Medicinal …, 2020 - ingentaconnect.com
Benzene is a six-membered hydrocarbon ring system and if three carbon-hydrogen units of
benzene ring are replaced by nitrogen atoms then triazine is formed. Triazines are present …

Effects of solvent casted poly (lactic acid)/poly (ethylene glycol)/paraben derivative triazine films on antibacterial performance and cytotoxicity

M Dandan Doganci, H Balci, D Davarcı… - Polymers for …, 2024 - Wiley Online Library
A series of poly (lactic acid)(PLA) films that including fully paraben substituted triazine
derivatives having anti‐bacterial properties have been prepared by utilizing the solvent …

CADD: Some Success Stories from Sanjeevini and the Way Forward

A Singh, S Shekhar, B Jayaram - Innovations and Implementations of …, 2021 - Springer
Sanjeevini, a comprehensive drug design software suite, has been developed for lead
molecule discovery taking off from protein and DNA as potential targets. Sanjeevini is a …

Synthesis of Novel 1, 2-Dihydro-1, 2, 4-Triazin-6 (5H)-one Derivatives as Anticancer Agents

T Verma, M Sinha, N Bansal - Current Bioactive Compounds, 2020 - ingentaconnect.com
Introduction: Cancer is still an untreatable disease and the second leading cause of death
globally. The heterocyclic compounds have always played a major role in the anticancer …

Synthesis and Investigation of the Antibacterial Activity of New Tris-Thiourea Derivatives

SS Ghorbani, N Montazeri, MM Zeydi… - Pharmaceutical Chemistry …, 2021 - Springer
An efficient procedure for the preparation of symmetrical tris-thiourea derivatives (5a–5h) by
means of one-pot condensation reaction between available benzoyl chlorides (1a–1h) with …

DNA interaction analysis with automated biosensor of paraben derivative s-triazines

E Şenkuytu, D Davarcı, Z Ölçer, GY Çiftçi - Journal of Molecular Structure, 2020 - Elsevier
Among all heterocyclic compounds, the triazine scaffold has an important place due to its
wide range of biological activities. Triazine has been preferred by many researchers as the …

Transferases and their inhibition

GL Patrick - Antimalarial Agents, 2020 - Elsevier
A number of Plasmodium falciparum transferase enzymes are being actively studied as
targets for potential antimalarial agents. Farnesytransferases catalyze the attachment of …