Peptide based antimicrobials: Design strategies and therapeutic potential
PK Hazam, R Goyal, V Ramakrishnan - Progress in biophysics and …, 2019 - Elsevier
Therapeutic activity of antibiotics is noteworthy, as they are used in the treatment of microbial
infections. Regardless of their utility, there has been a steep decrease in the number of drug …
infections. Regardless of their utility, there has been a steep decrease in the number of drug …
An atlas of anionic antimicrobial peptides from amphibians
SR Dennison, F Harris, M Mura… - Current Protein and …, 2018 - ingentaconnect.com
Anionic antimicrobial peptides (AAMPs) with net charges ranging from-1 to-8 have been
identified in frogs, toads, newts and salamanders across Africa, South America and China …
identified in frogs, toads, newts and salamanders across Africa, South America and China …
pH-responsive antimicrobial peptide with selective killing activity for bacterial abscess therapy
Z Wang, Q Li, J Li, L Shang, J Li, S Chou… - Journal of Medicinal …, 2022 - ACS Publications
The unusual acidic pH of the abscess milieu is an adverse factor that decreases the
therapeutic efficacy of traditional antibiotics. Moreover, avoiding both the undesired killing of …
therapeutic efficacy of traditional antibiotics. Moreover, avoiding both the undesired killing of …
Assessing barriers for antimicrobial penetration in complex asymmetric bacterial membranes: A case study with thymol
The bacterial cell envelope is a complex multilayered structure evolved to protect bacteria in
hostile environments. An understanding of the molecular basis for the interaction and …
hostile environments. An understanding of the molecular basis for the interaction and …
Growth-phase dependence of bacterial membrane lipid profile and labeling for in-cell solid-state NMR applications
F Laydevant, M Mahabadi, P Llido… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Cell labeling is a preliminary step in multiple biophysical approaches, including the solid-
state nuclear magnetic resonance (NMR) study of bacteria in vivo. Deuterium solid-state …
state nuclear magnetic resonance (NMR) study of bacteria in vivo. Deuterium solid-state …
The intricate link between membrane lipid structure and composition and membrane structural properties in bacterial membranes
It is now evident that the cell manipulates lipid composition to regulate different processes
such as membrane protein insertion, assembly and function. Moreover, changes in …
such as membrane protein insertion, assembly and function. Moreover, changes in …
Neutrons and model membranes: Moving towards complexity
G Fragneto, R Delhom, L Joly, E Scoppola - Current opinion in colloid & …, 2018 - Elsevier
Cells, the basic units of living organisms, are well delineated and separated from the
external environment by membranes. Capable of both enclosing the cellular constituents …
external environment by membranes. Capable of both enclosing the cellular constituents …
Targeting bacterial phospholipids and their synthesis pathways for antibiotic discovery
M Song, S Chen, W Lin, K Zhu - Progress in Lipid Research, 2024 - Elsevier
Bacterial infections in humans and animals caused by multidrug-resistant (MDR) pathogens
pose a serious threat to public health. New antibacterial targets are extremely urgent to …
pose a serious threat to public health. New antibacterial targets are extremely urgent to …
A Methylazanediyl Bisacetamide Derivative Sensitizes Staphylococcus aureus Persisters to a Combination of Gentamicin And Daptomycin
Infections caused by Staphylococcus aureus, notably methicillin‐resistant S. aureus
(MRSA), pose treatment challenges due to its ability to tolerate antibiotics and develop …
(MRSA), pose treatment challenges due to its ability to tolerate antibiotics and develop …
Phase Diagram for a Lysyl‐Phosphatidylglycerol Analogue in Biomimetic Mixed Monolayers with Phosphatidylglycerol: Insights into the Tunable Properties of …
C Wölk, H Youssef, T Guttenberg, H Marbach… - …, 2020 - Wiley Online Library
Ion pairing between the major phospholipids of the Staphylococcus aureus plasma
membrane (phosphatidylglycerol–PG and lysyl‐phosphatidylglycerol–LPG) confers …
membrane (phosphatidylglycerol–PG and lysyl‐phosphatidylglycerol–LPG) confers …