Lapachol treats non-alcoholic fatty liver disease by modulating the M1 polarization of Kupffer cells via PKM2
Y Yang, J Sheng, Y Sheng, J Wang, X Zhou… - International …, 2023 - Elsevier
Aim This study investigated the mechanism of action of lapachol (LAP) against non-alcoholic
fatty liver disease (NAFLD). Methods Primary Kupffer cells (KCs) of rats were used for in-vitro …
fatty liver disease (NAFLD). Methods Primary Kupffer cells (KCs) of rats were used for in-vitro …
The two alternative NADH:quinone oxidoreductases from Staphylococcus aureus: two players with different molecular and cellular roles
Staphylococcus aureus is an opportunistic pathogen that has emerged as a major public
health threat due to the increased incidence of its drug resistance. S. aureus presents a …
health threat due to the increased incidence of its drug resistance. S. aureus presents a …
[HTML][HTML] The monotopic quinone reductases from Staphylococcus aureus
Staphylococcus aureus, a Gram-positive bacterium, is an opportunistic pathogen and one of
the most frequent causes for community acquired and nosocomial infections that has …
the most frequent causes for community acquired and nosocomial infections that has …
Targeting Aspartate Transcarbamoylase: A Versatile Approach to Multispecies Drug and Herbicide Discovery
X Du - 2024 - research.rug.nl
This thesis primarily focuses on the identification and study of new drug target essential in
nucleic acid metabolism, specifically the catalytic step supported by aspartate …
nucleic acid metabolism, specifically the catalytic step supported by aspartate …