Bystander activation and autoimmunity
The interaction over time of genetic, epigenetic and environmental factors (ie, autoimmune
ecology) increases or decreases the liability an individual would have to develop an …
ecology) increases or decreases the liability an individual would have to develop an …
Bystander CD4+ T cells: crossroads between innate and adaptive immunity
T cells are the central mediators of both humoral and cellular adaptive immune responses.
Highly specific receptor-mediated clonal selection and expansion of T cells assure antigen …
Highly specific receptor-mediated clonal selection and expansion of T cells assure antigen …
Grip strength across the life course: normative data from twelve British studies
Introduction Epidemiological studies have shown that weaker grip strength in later life is
associated with disability, morbidity, and mortality. Grip strength is a key component of the …
associated with disability, morbidity, and mortality. Grip strength is a key component of the …
A Mycobacterium tuberculosis-specific subunit vaccine that provides synergistic immunity upon co-administration with Bacillus Calmette-Guérin
JS Woodworth, HS Clemmensen, H Battey… - Nature …, 2021 - nature.com
Given the encouraging clinical results of both candidate subunit vaccines and revaccination
with Bacillus Calmette-Guérin (BCG) against tuberculosis (TB), there is support for …
with Bacillus Calmette-Guérin (BCG) against tuberculosis (TB), there is support for …
Breaking tolerance to thyroid antigens: changing concepts in thyroid autoimmunity
SM McLachlan, B Rapoport - Endocrine reviews, 2014 - academic.oup.com
Thyroid autoimmunity involves loss of tolerance to thyroid proteins in genetically susceptible
individuals in association with environmental factors. In central tolerance, intrathymic …
individuals in association with environmental factors. In central tolerance, intrathymic …
Methodology and application of Escherichia coli F4 and F18 encoding infection models in post-weaning pigs
D Luise, C Lauridsen, P Bosi, P Trevisi - Journal of animal science and …, 2019 - Springer
The enterotoxigenic Escherichia coli (ETEC) expressing F4 and F18 fimbriae are the two
main pathogens associated with post-weaning diarrhea (PWD) in piglets. The growing …
main pathogens associated with post-weaning diarrhea (PWD) in piglets. The growing …
T cell co-stimulation and co-inhibition in cardiovascular disease: a double-edged sword
KH Simons, A de Jong, JW Jukema… - Nature Reviews …, 2019 - nature.com
The role of inflammation in cardiovascular disease (CVD) is now widely accepted. Immune
cells, including T cells, are influenced by inflammatory signals and contribute to the onset …
cells, including T cells, are influenced by inflammatory signals and contribute to the onset …
Airway inflammation and IgE production induced by dust mite allergen-specific memory/effector Th2 cell line can be effectively attenuated by IL-35
CD4+ memory/effector T cells play a central role in orchestrating the rapid and robust
immune responses upon re-encounter with specific Ags. However, the immunologic …
immune responses upon re-encounter with specific Ags. However, the immunologic …
Sex, age, and ethnic background shape adaptive immune responses induced by the SARS-CoV-2 mRNA vaccine
J Bai, A Chiba, G Murayama, T Kuga… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccine-induced
adaptive responses have been well investigated. However, the effects of sex, age, and …
adaptive responses have been well investigated. However, the effects of sex, age, and …
Triple jeopardy in ageing: COVID-19, co-morbidities and inflamm-ageing
IM Rea, HD Alexander - Ageing research reviews, 2022 - Elsevier
Covid-19 endangers lives, has disrupted normal life, changed the way medicine is practised
and is likely to alter our world for the foreseeable future. Almost two years on since the …
and is likely to alter our world for the foreseeable future. Almost two years on since the …