Multiple sclerosis (MS) is an immune mediated demyelinating disease of the central nervous
system (CNS). The importance of immune cells to MS pathology is supported by clinical data …

Global gene expression analysis using cDNA microarrays has proven to be a sensitive
method to gain insight into molecular pathways mediating multiple sclerosis (MS) activity …

Multiple sclerosis (MS) is an enigmatic disease of the central nervous system resulting in
sclerotic plaques with the pathological hallmarks of demyelination and axonal damage …

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS)
mediated by Th17 and Th1 cells. DNA microarray analysis previously showed that NR4A2 …

Background: Multiple Sclerosis (MS) involves an immune-mediated response in which
body's immune system destructs the protective sheath (myelin). Part of the known MS …

In this report we link candidate genes to complex behavioral phenotypes by using a
behavior genetics approach. Gene expression signatures were generated for the prefrontal …

Multiple sclerosis (MS) clusters with the so-called complex genetic diseases, a group of
common disorders characterized by modest disease risk heritability and multifaceted gene …

The complexity of MS is clearly reflected in the latest findings using global profiling methods.
Nevertheless, these new technologies are confirming some of the basic aspects of the …

Multiple sclerosis is the most frequent demyelinating disease in the human CNS
characterized by inflammation, demyelination, relative axonal loss and gliosis …

Cytokine gene polymorphisms are known to influence susceptibility and disease course of
many autoimmune diseases. Multiple sclerosis (MS) is a chronic autoimmune disease of the …