The human retina contains three types of glial cells: microglia and two types of macroglia,
astrocytes and Müller cells. Macroglia provide homeostatic and metabolic support to …

Resident microglial cells can be regarded as the immunological watchdogs of the brain and
the retina. They are active sensors of their neuronal microenvironment and rapidly respond …

The retina is an immune privileged tissue, which is protected from external and internal
insults by its blood-retina barriers and immune suppressive microenvironment. Apart from …

Microglia, the primary immune effector cells in the brain, continually monitor the tissue
parenchyma for pathological alterations and become activated in Alzheimer's disease. Loss …

Atrophic age‐related macular degeneration (AMD) is associated with the subretinal
accumulation of mononuclear phagocytes (MPs). Their role in promoting or inhibiting retinal …

Abstract Changes in microglial cell activation and distribution are associated with neuronal
decline in the central nervous system (CNS), particularly under pathological conditions …

Inflammation protects from dangerous stimuli, restoring normal tissue homeostasis.
Inflammatory response in the nervous system (“neuroinflammation”) has distinct features …

Purpose Microglia and Müller cells are prominent participants in retinal responses to injury
and disease that shape eventual tissue adaptation or damage. This investigation examined …

In the last decade, tremendous progress has been made in understanding the biology of
microglia–ie the fascinating immigrated resident immune cell population of the central …

In contrast to the tremendous amount of research data from the central nervous system,
relatively little is known about microglial homeostasis in the retina. This may be explained by …