As the first line of defence in the lung, alveolar macrophage contributes to maintaining lung
immune homoeostasis. Characterized by the heterogeneity and plasticity, macrophages …

Antibiotics have played a crucial role in the reduction in the incidence of TB globally as
evidenced by the fact that before the mid-20th century, the mortality rate within five years of …

Symbioses with microbes play a pivotal role in the evolutionary success of insects, and can
lead to intimate host–symbiont associations. However, how the host maintains a stable …

An important issue in the prognosis of tuberculosis (TB) is a short period between correct
diagnosis and start the suitable antibiotic therapy. So, a rapid and valid method for detection …

This work presents a new mathematical model that investigates the impact of diagnosis and
treatment of both latent tuberculosis infections and active cases on the transmission …

To the PE_PGRS protein subfamily belongs a group of surface-exposed mycobacterial
antigens that in Mycobacterium tuberculosis (Mtb) H37Rv accounts to more than 65 genes …

Pathogenic intracellular bacteria, parasites and viruses have evolved sophisticated
mechanisms to manipulate mammalian host cells to serve as niches for persistence and …

Since the first patent for micro array patches (MAPs) was filed in the 1970s, research on
utilising MAPs as a drug delivery system has progressed significantly, evidenced by the …

There is growing recognition that tuberculosis (TB) infection and disease exists as a
spectrum of states beyond the current binary classification of latent and active TB. Our aim …

Tuberculosis (TB), caused by the bacterial organism Mycobacterium tuberculosis, pose a
major threat to public health, especially in middle and low-income countries. Worldwide in …