[HTML][HTML] Endogenous viruses: Connecting recent and ancient viral evolution

P Aiewsakun, A Katzourakis - Virology, 2015 - Elsevier
The rapid rates of viral evolution allow us to reconstruct the recent history of viruses in great
detail. This feature, however, also results in rapid erosion of evolutionary signal within viral …

Endogenous retroviruses: acquisition, amplification and taming of genome invaders

M Dewannieux, T Heidmann - Current opinion in virology, 2013 - Elsevier
Highlights•Endogenous retroviruses as remnants of ancestral germline infections.•Ongoing
endogenisation of infectious retroviruses reported in some mammals.•Possible evolution …

Retroviral invasion of the koala genome

RE Tarlinton, J Meers, PR Young - Nature, 2006 - nature.com
Endogenous retroviruses are a common ancestral feature of mammalian genomes with most
having been inactivated over time through mutation and deletion. A group of more intact …

Transmission, evolution, and endogenization: lessons learned from recent retroviral invasions

AD Greenwood, Y Ishida, SP O'Brien… - Microbiology and …, 2018 - Am Soc Microbiol
Viruses of the subfamily Orthoretrovirinae are defined by the ability to reverse transcribe an
RNA genome into DNA that integrates into the host cell genome during the intracellular virus …

The piRNA response to retroviral invasion of the koala genome

T Yu, BS Koppetsch, S Pagliarani, S Johnston… - Cell, 2019 - cell.com
Summary Antisense Piwi-interacting RNAs (piRNAs) guide silencing of established
transposons during germline development, and sense piRNAs drive ping-pong amplification …

An infectious retrovirus susceptible to an IFN antiviral pathway from human prostate tumors

B Dong, S Kim, S Hong, J Das Gupta… - Proceedings of the …, 2007 - National Acad Sciences
We recently reported identification of a previously undescribed gammaretrovirus genome,
xenotropic murine leukemia virus-related virus (XMRV), in prostate cancer tissue from …

An exogenous retrovirus isolated from koalas with malignant neoplasias in a US zoo

W Xu, CK Stadler, K Gorman… - Proceedings of the …, 2013 - National Acad Sciences
Leukemia and lymphoma account for more than 60% of deaths in captive koalas
(Phascolarctos cinereus) in northeastern Australia. Although the endogenizing …

Real-time reverse transcriptase PCR for the endogenous koala retrovirus reveals an association between plasma viral load and neoplastic disease in koalas

R Tarlinton, J Meers, J Hanger… - Journal of general …, 2005 - microbiologyresearch.org
Koala retrovirus (KoRV) is a newly described endogenous retrovirus and is unusual in that
inserts comprise a full-length replication competent genome. As koalas are known to suffer …

Prevalence of koala retrovirus in geographically diverse populations in A ustralia

GS Simmons, PR Young, JJ Hanger… - Australian veterinary …, 2012 - Wiley Online Library
Objective To determine the prevalence of koala retrovirus (KoRV) in selected koala
populations and to estimate proviral copy number in a subset of koalas. Methods Blood or …

Infection with koala retrovirus subgroup B (KoRV-B), but not KoRV-A, is associated with chlamydial disease in free-ranging koalas (Phascolarctos cinereus)

CA Waugh, J Hanger, J Loader, A King, M Hobbs… - Scientific reports, 2017 - nature.com
The virulence of chlamydial infection in wild koalas is highly variable between individuals.
Some koalas can be infected (PCR positive) with Chlamydia for long periods but remain …