Anti‐inflammatory agents in the treatment of bipolar depression: a systematic review and meta‐analysis
Objective Inflammation has been implicated in the risk, pathophysiology, and progression of
mood disorders and, as such, has become a target of interest in the treatment of bipolar …
mood disorders and, as such, has become a target of interest in the treatment of bipolar …
Revisiting inflammation in bipolar disorder
Bipolar disorder (BD) has been associated with immune changes, and yet their underlying
mechanisms are still not fully understood. Here, we review the current state of the field …
mechanisms are still not fully understood. Here, we review the current state of the field …
A meta-analysis of blood cytokine network alterations in psychiatric patients: comparisons between schizophrenia, bipolar disorder and depression
DR Goldsmith, MH Rapaport, BJ Miller - Molecular psychiatry, 2016 - nature.com
Schizophrenia, bipolar disorder and major depressive disorder (MDD) have all been
associated with aberrant blood cytokine levels; however, neither the pattern of cytokine …
associated with aberrant blood cytokine levels; however, neither the pattern of cytokine …
Meta-analysis of cerebrospinal fluid cytokine and tryptophan catabolite alterations in psychiatric patients: comparisons between schizophrenia, bipolar disorder, and …
AK Wang, BJ Miller - Schizophrenia bulletin, 2018 - academic.oup.com
Introduction: Schizophrenia, bipolar disorder, and major depressive disorder (MDD) have all
been associated with immune system dysfunction, including aberrant cerebrospinal fluid …
been associated with immune system dysfunction, including aberrant cerebrospinal fluid …
Bipolar disorder and inflammation
JD Rosenblat, RS McIntyre - Psychiatric Clinics, 2016 - psych.theclinics.com
Methods For this narrative clinical overview, the MEDLINE/PubMed, Embase, Google
Scholar and ClinicalTrials. gov databases were searched from inception through June 2015 …
Scholar and ClinicalTrials. gov databases were searched from inception through June 2015 …
[HTML][HTML] Neuropathology of mood disorders: do we see the stigmata of inflammation?
N Mechawar, J Savitz - Translational psychiatry, 2016 - nature.com
A proportion of cases with mood disorders have elevated inflammatory markers in the blood
that conceivably may result from stress, infection and/or autoimmunity. However, it is not yet …
that conceivably may result from stress, infection and/or autoimmunity. However, it is not yet …
Effects of psychotropic drugs on inflammation: consequence or mediator of therapeutic effects in psychiatric treatment?
D Baumeister, S Ciufolini, V Mondelli - Psychopharmacology, 2016 - Springer
Rationale Current psychotropic medications have been shown to modulate immune
activation. However, the effects of individual psychotropic agents on the immune system and …
activation. However, the effects of individual psychotropic agents on the immune system and …
Neuroinflammation and cognition across psychiatric conditions
Cognitive impairments reported across psychiatric conditions (ie, major depressive disorder,
bipolar disorder, schizophrenia, and posttraumatic stress disorder) strongly impair the …
bipolar disorder, schizophrenia, and posttraumatic stress disorder) strongly impair the …
[HTML][HTML] Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive …
K Recourt, P de Boer, P van der Ark, H Benes… - Translational …, 2023 - nature.com
JNJ-54175446 is a selective purine P2X7 receptor (P2X7R) antagonist that attenuates
microglial IL-1β/IL-18 release. In healthy volunteers, JNJ-54175446 suppressed peripheral …
microglial IL-1β/IL-18 release. In healthy volunteers, JNJ-54175446 suppressed peripheral …
A comparison of the neutrophil-lymphocyte, platelet-lymphocyte and monocyte-lymphocyte ratios in schizophrenia and bipolar disorder patients–a retrospective file …
S Özdin, G Sarisoy, Ö Böke - Nordic journal of psychiatry, 2017 - Taylor & Francis
Abstract Neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR) and monocyte-
lymphocyte ratio (MLR) have recently been used as indicators of inflammation. Higher MLR …
lymphocyte ratio (MLR) have recently been used as indicators of inflammation. Higher MLR …