Membrane and nuclear estrogen receptor alpha actions: from tissue specificity to medical implications
JF Arnal, F Lenfant, R Metivier, G Flouriot… - Physiological …, 2017 - journals.physiology.org
Estrogen receptor alpha (ERα) has been recognized now for several decades as playing a
key role in reproduction and exerting functions in numerous nonreproductive tissues. In this …
key role in reproduction and exerting functions in numerous nonreproductive tissues. In this …
[HTML][HTML] Estrogen receptor beta (ERβ): a ligand activated tumor suppressor
R Mal, A Magner, J David, J Datta… - Frontiers in …, 2020 - frontiersin.org
Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) belong to a superfamily of
nuclear receptors called steroid hormone receptors, which, upon binding ligand, dimerize …
nuclear receptors called steroid hormone receptors, which, upon binding ligand, dimerize …
Sp transcription factor family and its role in cancer
S Safe, M Abdelrahim - European journal of cancer, 2005 - Elsevier
Specificity protein 1 (Sp1) and other Sp and Krüppel-like factor (KLF) proteins are members
of a family of transcription factors which bind GC/GT-rich promoter elements through three …
of a family of transcription factors which bind GC/GT-rich promoter elements through three …
[HTML][HTML] Nonclassical genomic ER/Sp and ER/AP-1 signaling pathways
Abstract 17β-Estradiol (E2) binds to the estrogen receptor (ER) to activate gene expression
or repression and this involves both genomic (nuclear) and non-genomic (extranuclear …
or repression and this involves both genomic (nuclear) and non-genomic (extranuclear …
Gene regulation by Sp1 and Sp3
L Li, S He, JM Sun, JR Davie - Biochemistry and Cell Biology, 2004 - cdnsciencepub.com
La famille de facteurs de transcription Sp partage une combinaison particulière de trois
motifs à doigts de zinc Cys2His2 qui forment le domaine spécifique de liaison à l'ADN. Au …
motifs à doigts de zinc Cys2His2 qui forment le domaine spécifique de liaison à l'ADN. Au …
The role of estrogens and estrogen receptors in normal prostate growth and disease
GS Prins, KS Korach - Steroids, 2008 - Elsevier
Estrogens have significant direct and indirect effects on prostate gland development and
homeostasis and have been long suspected in playing a role in the etiology of prostatic …
homeostasis and have been long suspected in playing a role in the etiology of prostatic …
Genome-wide analysis of estrogen receptor α DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional …
JD Stender, K Kim, TH Charn, B Komm… - … and cellular biology, 2010 - Am Soc Microbiol
Nuclear receptor estrogen receptor alpha (ERα) controls the expression of hundreds of
genes responsible for target cell phenotypic properties, but the relative importance of direct …
genes responsible for target cell phenotypic properties, but the relative importance of direct …
General molecular biology and architecture of nuclear receptors
Nuclear receptors (NRs) regulate and coordinate multiple processes by integrating internal
and external signals, thereby maintaining homeostasis in front of nutritional, behavioral and …
and external signals, thereby maintaining homeostasis in front of nutritional, behavioral and …
[HTML][HTML] Zinc and cancer: implications for LIV-1 in breast cancer
BJ Grattan, HC Freake - Nutrients, 2012 - mdpi.com
Zinc is a trace mineral which is vital for the functioning of numerous cellular processes, is
critical for growth, and may play an important role in cancer etiology and outcome. The …
critical for growth, and may play an important role in cancer etiology and outcome. The …
Estrogen receptor α represses transcription of HBV genes via interaction with hepatocyte nuclear factor 4α
SH Wang, SH Yeh, WH Lin, KH Yeh, Q Yuan, NS Xia… - Gastroenterology, 2012 - Elsevier
BACKGROUND & AIMS: Women with hepatitis B virus (HBV) infection usually have lower
viral loads than men, reducing their risk of liver cancer. There are 2 androgen-responsive …
viral loads than men, reducing their risk of liver cancer. There are 2 androgen-responsive …