Estrogen receptor alpha (ERα) has been recognized now for several decades as playing a
key role in reproduction and exerting functions in numerous nonreproductive tissues. In this …

Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) belong to a superfamily of
nuclear receptors called steroid hormone receptors, which, upon binding ligand, dimerize …

Specificity protein 1 (Sp1) and other Sp and Krüppel-like factor (KLF) proteins are members
of a family of transcription factors which bind GC/GT-rich promoter elements through three …

Abstract 17β-Estradiol (E2) binds to the estrogen receptor (ER) to activate gene expression
or repression and this involves both genomic (nuclear) and non-genomic (extranuclear …

La famille de facteurs de transcription Sp partage une combinaison particulière de trois
motifs à doigts de zinc Cys2His2 qui forment le domaine spécifique de liaison à l'ADN. Au …

Estrogens have significant direct and indirect effects on prostate gland development and
homeostasis and have been long suspected in playing a role in the etiology of prostatic …

Nuclear receptor estrogen receptor alpha (ERα) controls the expression of hundreds of
genes responsible for target cell phenotypic properties, but the relative importance of direct …

Nuclear receptors (NRs) regulate and coordinate multiple processes by integrating internal
and external signals, thereby maintaining homeostasis in front of nutritional, behavioral and …

Zinc is a trace mineral which is vital for the functioning of numerous cellular processes, is
critical for growth, and may play an important role in cancer etiology and outcome. The …

BACKGROUND & AIMS: Women with hepatitis B virus (HBV) infection usually have lower
viral loads than men, reducing their risk of liver cancer. There are 2 androgen-responsive …